ApoB:ApoA1 Ratio

What is the ApoB:ApoA1 ratio?

The ApoB/ApoA1 ratio is highly valuable for detecting atherogenic (plaque-filled artery) risk. The ApoB/ApoA1 ratio is stronger than the total cholesterol/HDL cholesterol and LDL/HDL cholesterol ratios in predicting risk. The lower the ApoB/ApoA1 ratio, the lower the risk. Learn more about ApoB and ApoA1.

How can I better understand my results?

Several studies have defined certain ApoB:ApoA1 levels as markers for disease (ex. papers on metabolic syndromecoronary artery disease, coronary heart disease, all-cause mortality, to list a few). The general consensus based on literature is that an optimal ApoB:ApoA1 ratio is < 0.8 to minimize the risk of disease onset.

Cleveland Heart Lab defines low-, moderate-, and high-risk values for adults as the following:

 Sex Low Risk Moderate Risk High Risk
Male < 0.77 0.77 - 0.95 > 0.95
Female < 0.63 0.63 - 0.78 > 0.78

 

If your ApoB:ApoA1 levels are high, you can try:

  • Following a Mediterranean diet
  • Following a vegan diet
  • Consuming more fermented dairy products
  • Limiting sugar intake
  • Increasing protein intake
  • Incorporating more polyunsaturated fats (omega-3 and omega-6)
  • Maintaining adequate vitamin D, vitamin C, and magnesium levels

Regular exercise and improving sleep hygiene may also alter unfavorable apolipoprotein profiles. If you are concerned with any of your results, please consult with our physician.

Where can I learn more?

Mayo Clinic Labs - ApoA1 and B

Frontrow Health - Apolipoprotein B/A1 Ratio

 

DISCLAIMER: IF YOU ARE CONCERNED WITH ANY OF YOUR RESULTS, PLEASE CONSULT WITH YOUR PHYSICIAN.