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What is insulin?

InsulinĀ is a hormone secreted primarily by the pancreas that is mainly responsible for regulating blood glucose levels. After eating, insulin is released toĀ initiate the usage and storage of glucose.Ā 

Why is fasting insulin important?

According to theĀ CDC, about 1 in 10 Americans have diabetes, and about 1 in 5 people with diabetes donā€™t know they have it! High insulin levels can be a leading indicator of pre-diabetes and metabolic syndrome.Ā TypeĀ 1 diabetesĀ is an autoimmune disease caused byĀ insufficient production of insulin by the pancreas, whereasĀ type 2 diabetesĀ is a metabolic disease caused by insulin resistance to high levels of circulating glucose.Ā Gestational diabetesĀ isĀ another type that developsĀ in pregnant women and can have negative implications forĀ the health of the baby. While insulin is a necessary data point for those with diabetes, it is also very useful for users without these concerns. Insulin levels can serve as a great indicator of your bodyā€™s reaction to your current diet and lifestyle. Because of its significance to metabolic health, insulin is included inĀ SiPhox Healthā€˜s base panel.

How can I better understand my insulin levels?

Insulin follows a naturalĀ circadian rhythm,Ā so sticking to aĀ routine (e.g. eating at the same time every day) can help maintain optimal metabolic levels throughout the day.

Make sure your insulin levelsĀ are within the recommendedĀ rangeĀ if you take your test without fasting. We recommend you test in a fasted state (no food or beverages besides water for 8 hours prior to testing).

WhenĀ fasting, you can expect the following insulin levels:

  • Low: <1.9 uIU/mL
  • Optimal:Ā 1.9-8Ā uIU/mL
  • High: 8-23 uIU/mL
  • Very high: >23 uIU/mL

Fasting insulin levels that are higher than normal can be indicative of insulin resistance.Ā Insulin resistanceĀ is when the body fails to respond to insulin by taking up glucose, soĀ moreĀ insulinĀ is secreted to compensate. Due to the natural rise and fall of insulin throughout the day in anticipation of food, the time of day and your fasting state can influence results. Consult with your physician if you are concerned about your insulin levels.Ā 

SymptomsĀ of insulin resistance include:

  • Increased thirst
  • Frequent urination
  • Increased hunger
  • Blurred vision or eye changes
  • Headaches
  • Vaginal and skin infections
  • Slow-healing cuts and sores
  • Darkened skin in your armpit, back, or sides of your neck (acanthosis nigricans)
  • Skin tags

How can I maintain optimal insulin levels?

If you need to maintain or adjust your insulin levels, consider the following strategies:

Dietary Changes: Avoid highly processed, high-carbohydrate foods and saturated fats and opt for low glycemic index foods (beans and legumes, non-starchy veggies, berries, etc.) to lower insulin levels.

Lifestyle Changes: Try exercising and losing weight by leading a healthy lifestyle to regulate insulin levels.

Hormonal disorders such as Cushingā€™s syndrome, acromegaly, hypothyroidism, and genetic disorders can cause insulin resistance. Certain medications can cause insulin resistance as well, which is why you should consult with your physician if you are concerned about your levels.

Where can I learn more?

DISCLAIMER: IF YOU ARE CONCERNED WITH ANY OF YOUR RESULTS, PLEASE CONSULT WITH YOUR PHYSICIAN.