Comprehensive at-home health testing. Fast. Painless. Accurate.

Only $124.

Learn More
HSA/FSA Eligible
EasyDraw character
logo
Partner With UsPartnerStart Testing

Is it bad to have low triglycerides?

While high triglycerides are a known health risk, very low levels (under 40 mg/dL) can indicate malnutrition, hyperthyroidism, or genetic conditions. Most people with moderately low triglycerides (40-60 mg/dL) have no health issues, but monitoring is important.

Questions on this topic?Ask Sai, our AI longevity expert.
Ask Sai

Understanding Triglycerides and Their Role in Your Body

Triglycerides are the most common type of fat in your body, serving as a crucial energy source and playing vital roles in various bodily functions. When you eat, your body converts calories it doesn't immediately need into triglycerides, which are then stored in fat cells and released between meals when your body needs energy.

While much attention is given to high triglyceride levels and their association with heart disease, metabolic syndrome, and pancreatitis, the question of whether low triglycerides can be problematic often goes unaddressed. Understanding both ends of the triglyceride spectrum is essential for comprehensive health management.

What Are Considered Low Triglyceride Levels?

Normal triglyceride levels typically fall below 150 mg/dL, with optimal levels considered to be under 100 mg/dL. However, when triglyceride levels drop below certain thresholds, they may be considered abnormally low:

  • Below 150 mg/dL: Normal range
  • Below 100 mg/dL: Often optimal in healthy individuals
  • Below 50 mg/dL: May warrant evaluation if accompanied by symptoms
  • Below 35 mg/dL: Should be evaluated for underlying causes

It's important to note that there isn't a universal consensus on what constitutes 'too low' for triglycerides. The clinical significance of low triglycerides depends heavily on your overall health status, symptoms, and underlying medical conditions. Regular monitoring through comprehensive lipid panels can help track your levels over time.

Common Causes of Low Triglycerides

Dietary Factors

One of the most common causes of low triglycerides is dietary restriction or malnutrition. This can occur due to:

  • Very low-fat diets
  • Extreme calorie restriction
  • Eating disorders such as anorexia nervosa
  • Malabsorption disorders affecting fat absorption
  • Following extremely restrictive diets without proper nutritional guidance

Medical Conditions

Several medical conditions can lead to abnormally low triglyceride levels:

  • Hyperthyroidism (overactive thyroid)
  • Malabsorption syndromes (celiac disease, Crohn's disease)
  • Liver disease affecting lipid metabolism
  • Certain genetic conditions like abetalipoproteinemia
  • Some autoimmune conditions

Medications and Supplements

Certain medications and supplements can lower triglyceride levels, sometimes to below-normal ranges:

  • High-dose omega-3 fatty acid supplements
  • Fibrate medications (used to treat high triglycerides)
  • Niacin (vitamin B3) in therapeutic doses
  • Some cholesterol-lowering medications
  • Certain antibiotics and antifungal medications

Health Implications of Low Triglycerides

The relationship between triglyceride levels and health outcomes is complex and context-dependent. While moderately low triglycerides within the normal range (typically 50-100 mg/dL) may indicate good metabolic health in healthy individuals, very low levels can sometimes signal underlying health issues requiring medical attention.

Potential Benefits

Research suggests that lower triglyceride levels within the normal range are generally associated with:

  • In healthy individuals: Triglycerides in the lower normal range (50-100 mg/dL) may reflect good diet, exercise habits, and metabolic health
  • Cardiovascular protection: Lower triglycerides within normal ranges are associated with reduced risk of heart disease, metabolic syndrome, and pancreatitis
  • Metabolic benefits: May correlate with better insulin sensitivity and reduced inflammation

Potential Concerns

When triglycerides drop too low, particularly below 40 mg/dL, potential concerns include:

  • Nutritional deficiencies, especially fat-soluble vitamins (A, D, E, K)
  • Hormonal imbalances affecting reproductive health
  • Compromised immune function
  • Difficulty maintaining body temperature
  • Potential cognitive effects due to inadequate fat intake
Biomarker Blueprint: The Science of Living Well, Longer
Free Ebook

The Science of Living Well, Longer

Co-authored with Michael Lustgarten, Ph.D. Discover biomarkers that predict healthy aging and add years to your life.

  • The critical difference between lifespan and healthspan
  • Which biomarkers predict healthy aging at every life stage
  • Evidence-based strategies that add years to your life
  • How to create your personalized longevity roadmap

We respect your privacy. Unsubscribe anytime.

Symptoms Associated with Low Triglycerides

Low triglycerides themselves rarely cause symptoms directly. Instead, symptoms typically arise from the underlying condition causing the low levels. Common symptoms that may accompany very low triglycerides include:

  • Unexplained weight loss
  • Chronic fatigue or weakness
  • Difficulty concentrating or brain fog
  • Dry skin and hair
  • Irregular menstrual cycles in women
  • Digestive issues or chronic diarrhea
  • Feeling cold frequently

If you're experiencing these symptoms along with low triglyceride levels, it's important to work with a healthcare provider to identify and address the root cause.

When to See a Healthcare Provider

You should consult with a healthcare provider if:Your triglycerides are consistently below 40 mg/dL

  • You have symptoms suggesting malnutrition or malabsorption
  • You're experiencing unexplained weight loss
  • You have a family history of lipid disorders
  • You're taking medications that affect lipid levels
  • You follow a very restrictive diet

Your healthcare provider may recommend additional testing to identify underlying causes, including thyroid function tests, liver panels, and nutritional assessments.

Managing and Monitoring Low Triglycerides

Dietary Adjustments

If low triglycerides are due to inadequate dietary fat intake, consider:

  • Including healthy fats from sources like avocados, nuts, seeds, and olive oil
  • Ensuring adequate caloric intake to meet your body's needs
  • Working with a registered dietitian if following a restrictive diet
  • Supplementing with fat-soluble vitamins if recommended by your provider

Regular Monitoring

Regular blood testing can help track your triglyceride levels alongside other important health markers. Comprehensive metabolic panels that include lipid profiles, thyroid function, and other biomarkers provide a complete picture of your health status.

Addressing Underlying Conditions

Treatment should focus on addressing any underlying conditions causing low triglycerides:

  • Managing hyperthyroidism with appropriate medications
  • Treating malabsorption disorders
  • Adjusting medications that may be lowering triglycerides excessively
  • Addressing any eating disorders with professional support

The Bottom Line on Low Triglycerides

While high triglycerides are a well-established cardiovascular risk factor, low triglycerides are generally not harmful for most people. In fact, triglyceride levels on the lower end of the normal range (50-100 mg/dL) are often associated with better metabolic health. However, very low levels (below 40 mg/dL) warrant investigation, as they may indicate malnutrition, malabsorption, or other underlying health conditions.

The key is understanding your individual health context. Triglyceride levels should always be interpreted within the context of your complete health picture, including other lipid levels, medical history, and overall clinical presentation. Work with your healthcare provider to understand what your specific triglyceride levels mean for your individual health.

References

  1. Nordestgaard, B. G. (2016). Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology. Circulation Research, 118(4), 547-563.[PubMed][DOI]
  2. Miller, M., Stone, N. J., Ballantyne, C., Bittner, V., Criqui, M. H., Ginsberg, H. N., ... & Pennathur, S. (2011). Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation, 123(20), 2292-2333.[PubMed][DOI]
  3. Langsted, A., & Nordestgaard, B. G. (2019). Nonfasting versus fasting lipid profile for cardiovascular risk prediction. Pathology, 51(2), 131-141.[PubMed][DOI]
  4. Ramasamy, I. (2018). Update on the molecular biology of dyslipidemias. Clinica Chimica Acta, 454, 143-185.[PubMed][DOI]
  5. Liu, Y., Chen, S., Zühlke, L., et al. (2025). Triglyceride levels and its association with all-cause mortality and cardiovascular outcomes among patients with heart failure. Nature Communications, 16, 679.
  6. Sarwar, N., Sandhu, M. S., Ricketts, S. L., et al. (2010). Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. The Lancet, 375(9726), 1634-1639.

Was this article helpful?

Frequently Asked Questions

How can I test my triglycerides at home?

You can test your triglycerides at home with SiPhox Health's Heart & Metabolic Program. This CLIA-certified program includes triglyceride testing along with comprehensive cardiovascular and metabolic biomarkers, providing lab-quality results from the comfort of your home.

What is the ideal triglyceride level?

The ideal triglyceride level is generally considered to be below 100 mg/dL, with normal levels being under 150 mg/dL. Levels between 50-100 mg/dL are typically optimal for most people. Very low levels below 40 mg/dL may warrant investigation for underlying causes.

Can diet alone cause low triglycerides?

Yes, diet can significantly impact triglyceride levels. Very low-fat diets, extreme calorie restriction, or malnutrition can cause triglycerides to drop below normal ranges. A balanced diet with healthy fats is important for maintaining appropriate triglyceride levels.

How often should I check my triglyceride levels?

For most adults, checking triglycerides annually as part of a lipid panel is sufficient. However, if you have abnormal levels, are on medications affecting lipids, or have risk factors for heart disease, your healthcare provider may recommend testing every 3-6 months.

Are low triglycerides linked to any serious health conditions?

While moderately low triglycerides are generally not concerning, very low levels can be associated with hyperthyroidism, malabsorption disorders, liver disease, or certain genetic conditions. They may also indicate inadequate nutrition or eating disorders.

This article is licensed under CC BY 4.0. You are free to share and adapt this material with attribution.

Ask Questions About Any Health Topic

Chat with Sai, our AI health assistant, for personalized insights.

Click or drag file to upload blood test results

Backed by leading experts in health optimization

Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations
Jordan Isenberg, MD

Jordan Isenberg, MD

Chief Medical Officer
Daniel Kaplan, PhD

Daniel Kaplan, PhD

Director of Assay Development
Paul Thompson, MD

Paul Thompson, MD

Advisor, Cardiology
Pika Ksela, MD

Pika Ksela, MD

Health Programs Lead
David Nguyen, MD

David Nguyen, MD

Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations
Jordan Isenberg, MD

Jordan Isenberg, MD

Chief Medical Officer
Daniel Kaplan, PhD

Daniel Kaplan, PhD

Director of Assay Development
Paul Thompson, MD

Paul Thompson, MD

Advisor, Cardiology
Pika Ksela, MD

Pika Ksela, MD

Health Programs Lead
David Nguyen, MD

David Nguyen, MD

Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations
Jordan Isenberg, MD

Jordan Isenberg, MD

Chief Medical Officer
Daniel Kaplan, PhD

Daniel Kaplan, PhD

Director of Assay Development
Paul Thompson, MD

Paul Thompson, MD

Advisor, Cardiology
Pika Ksela, MD

Pika Ksela, MD

Health Programs Lead
David Nguyen, MD

David Nguyen, MD

Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations
Jordan Isenberg, MD

Jordan Isenberg, MD

Chief Medical Officer
Daniel Kaplan, PhD

Daniel Kaplan, PhD

Director of Assay Development
Paul Thompson, MD

Paul Thompson, MD

Advisor, Cardiology
Pika Ksela, MD

Pika Ksela, MD

Health Programs Lead
David Nguyen, MD

David Nguyen, MD

Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations
Jordan Isenberg, MD

Jordan Isenberg, MD

Chief Medical Officer
Daniel Kaplan, PhD

Daniel Kaplan, PhD

Director of Assay Development
Paul Thompson, MD

Paul Thompson, MD

Advisor, Cardiology
Pika Ksela, MD

Pika Ksela, MD

Health Programs Lead
David Nguyen, MD

David Nguyen, MD

Advisor, Hematology and Cancer Prevention

Our mission is to empower everyday people to test their blood biomarkers painlessly at home and live healthier, longer.

Company
SiPhox, Inc.
111 Terrace Hall Avenue, Burlington
MA 01803 US

The reference ranges and insights presented in the SiPhox Health dashboard are meant to improve readability and provide context, however you should consult with your physician for a more formal interpretation of your results. No communication from SiPhox Health is meant to be or should be taken as medical advice. SiPhox Health is a wellness-only service and is not designed to diagnose, prevent, or treat any disease. If you are concerned about any of the data in your dashboard please consult your physician immediately.

SiPhox Health mail-in testing is fulfilled and provided by third parties, in compliance with laboratory-developed test regulations.

LegitScript approvedCLIA CertifiedCAP AccreditedLegitScript approved