Why do I have frequent skin infections?

Frequent skin infections often result from weakened immunity, underlying conditions like diabetes, poor hygiene, or skin barrier damage. Testing key biomarkers like glucose, vitamin D, and inflammatory markers can help identify root causes and guide effective treatment.

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Understanding Frequent Skin Infections

If you're dealing with recurring skin infections, you're not alone. These persistent problems can be frustrating, painful, and sometimes embarrassing. While occasional skin infections are common, frequent recurrences often signal an underlying issue that needs attention. Understanding why your body seems more susceptible to these infections is the first step toward breaking the cycle.

Skin infections occur when harmful microorganisms like bacteria, fungi, or viruses breach your skin's natural defenses and multiply. Your skin normally acts as an effective barrier, but when this defense system is compromised or your immune system isn't functioning optimally, infections can take hold more easily. The key to addressing frequent infections lies in identifying and treating both the immediate infection and its root causes.

Common Types of Recurring Skin Infections

Bacterial Infections

Bacterial skin infections are among the most common types people experience repeatedly. Staphylococcus aureus (staph) and Streptococcus (strep) are the usual culprits. These can manifest as:

Common Fungal Infections: Recognition and Treatment

Fungal infections often recur without complete treatment and environmental management.
Infection TypeCommon LocationsKey SymptomsTreatment Approach
Athlete's FootAthlete's FootBetween toes, foot solesItching, scaling, crackingTopical antifungals, keep feet dry
RingwormRingwormScalp, body, groinRed, circular rash with clear centerOral or topical antifungals
CandidaCandida/YeastSkin folds, mouth, genitalsRed rash, white patches, itchingAntifungal creams, address underlying causes
Nail FungusNail FungusToenails, fingernailsThickened, discolored nailsOral antifungals, long-term treatment

Fungal infections often recur without complete treatment and environmental management.

  • Cellulitis: Deep skin and tissue infection causing redness, warmth, and swelling
  • Impetigo: Highly contagious infection with honey-crusted lesions
  • Folliculitis: Infection of hair follicles appearing as small red bumps
  • Boils and abscesses: Painful, pus-filled lumps under the skin
  • MRSA infections: Antibiotic-resistant staph infections that are harder to treat

Fungal Infections

Fungal infections thrive in warm, moist environments and can be particularly persistent. Common recurring fungal infections include athlete's foot, ringworm, jock itch, and candida (yeast) infections. These infections often return because the fungal spores can survive on surfaces and in fabrics, making complete eradication challenging.

Viral Infections

Certain viral skin infections can recur, particularly in people with weakened immune systems. Herpes simplex (cold sores), shingles (reactivated chickenpox virus), and molluscum contagiosum are examples of viral infections that may repeatedly affect the skin.

Major Causes of Frequent Skin Infections

Immune System Dysfunction

Your immune system is your body's primary defense against infections. When it's not functioning properly, you become more susceptible to recurring infections. Several factors can compromise immune function:

  • Primary immunodeficiency disorders (genetic conditions affecting immune cells)
  • Secondary immunodeficiency from medications (steroids, chemotherapy, immunosuppressants)
  • HIV/AIDS
  • Chronic stress and poor sleep
  • Nutritional deficiencies, particularly vitamin D, zinc, and vitamin C
  • Age-related immune decline

If you suspect immune dysfunction might be contributing to your frequent infections, comprehensive biomarker testing can reveal important clues about your immune health status. Key markers like vitamin D levels, inflammatory markers, and complete blood counts can provide valuable insights into your body's defense capabilities.

Diabetes and Blood Sugar Issues

Diabetes and prediabetes significantly increase the risk of skin infections. High blood sugar levels create an environment where bacteria and fungi thrive while simultaneously impairing immune function. People with diabetes often experience:

  • Reduced blood flow to skin tissues
  • Nerve damage affecting sensation and healing
  • Impaired white blood cell function
  • Delayed wound healing
  • Increased glucose in skin tissues feeding microorganisms

Even without diagnosed diabetes, blood sugar fluctuations can impact your susceptibility to infections. Regular monitoring of HbA1c, fasting glucose, and other metabolic markers can help identify whether blood sugar issues are contributing to your recurring infections.

Environmental and Lifestyle Factors

Your daily habits and environment play crucial roles in skin infection frequency. Poor hygiene practices, while obvious, aren't the only lifestyle factors to consider. Excessive washing can actually damage your skin barrier, making infections more likely. Other important factors include:

  • Exposure to contaminated surfaces (gym equipment, shared towels)
  • Tight, non-breathable clothing creating moist environments
  • Occupational hazards (healthcare workers, athletes, manual laborers)
  • Living in crowded conditions
  • Pet exposure without proper hygiene
  • Swimming in contaminated water
  • Sharing personal items like razors or towels

Skin Barrier Dysfunction

Your skin barrier is your first line of defense against infections. When this barrier is compromised, microorganisms can more easily penetrate and cause infections. Conditions that damage the skin barrier include:

  • Eczema (atopic dermatitis)
  • Psoriasis
  • Chronic dry skin
  • Frequent use of harsh soaps or chemicals
  • Burns or injuries
  • Surgical wounds
  • Excessive scratching or picking at skin

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Medical Conditions Linked to Recurring Infections

Several medical conditions beyond diabetes can increase your susceptibility to skin infections. Understanding these connections can help you and your healthcare provider develop a more comprehensive treatment approach.

Hormonal Imbalances

Hormonal fluctuations can affect your skin's oil production, pH balance, and immune response. Conditions like polycystic ovary syndrome (PCOS), thyroid disorders, and hormonal changes during pregnancy or menopause can all increase infection risk. Cortisol imbalances from chronic stress or adrenal issues can also suppress immune function, making infections more likely.

If you're experiencing other symptoms alongside frequent infections, such as unexplained weight changes, fatigue, or irregular periods, hormone testing might reveal important connections. Understanding your hormone levels can guide targeted interventions to reduce infection frequency.

Circulatory Problems

Poor circulation reduces oxygen and nutrient delivery to skin tissues while impairing the removal of waste products. This creates an environment where infections can more easily establish and persist. Conditions affecting circulation include peripheral artery disease, venous insufficiency, and lymphedema. People with these conditions often experience infections in their lower extremities where circulation is poorest.

Diagnostic Testing for Frequent Infections

Identifying the root cause of frequent skin infections often requires comprehensive testing. Your healthcare provider may recommend various tests to uncover underlying issues:

  • Complete blood count (CBC) to check immune cell levels
  • Fasting glucose and HbA1c for diabetes screening
  • Vitamin D, B12, and other nutrient levels
  • Thyroid function tests (TSH, Free T3, Free T4)
  • Inflammatory markers (CRP, ESR)
  • Immunoglobulin levels
  • HIV testing if risk factors present
  • Skin cultures to identify specific pathogens
  • Allergy testing for environmental triggers

For a comprehensive analysis of your existing blood test results and personalized insights into potential causes of your frequent infections, you can use SiPhox Health's free upload service. This service translates complex lab results into clear, actionable recommendations tailored to your unique health profile.

Treatment Strategies and Prevention

Immediate Treatment Approaches

Treating active infections promptly and completely is crucial to prevent spread and reduce recurrence risk. Treatment depends on the type of infection but may include topical or oral antibiotics for bacterial infections, antifungal medications for fungal infections, or antiviral drugs for certain viral infections. Completing the full course of prescribed medication is essential, even if symptoms improve quickly.

Long-term Prevention Strategies

Preventing future infections requires addressing underlying causes while maintaining good skin health. Effective prevention strategies include:

  • Optimizing blood sugar control through diet and exercise
  • Maintaining proper skin hygiene without over-washing
  • Using gentle, pH-balanced cleansers
  • Keeping skin moisturized to maintain barrier function
  • Wearing breathable fabrics and changing out of wet clothes promptly
  • Disinfecting shared surfaces and equipment
  • Managing stress through relaxation techniques
  • Getting adequate sleep (7-9 hours nightly)
  • Staying current with vaccinations

Nutritional support plays a vital role in immune function and skin health. Focus on consuming adequate protein for tissue repair, vitamin C for collagen production, zinc for wound healing, and vitamin D for immune regulation. Probiotics may also help by supporting beneficial bacteria that compete with harmful microorganisms.

When to Seek Medical Help

While minor skin infections can sometimes be managed at home, certain situations require prompt medical attention. Seek immediate care if you experience:

  • Fever or chills accompanying skin infection
  • Red streaks extending from the infected area
  • Rapidly spreading redness or swelling
  • Severe pain or tenderness
  • Pus or foul-smelling discharge
  • Infections that don't improve within 48-72 hours of treatment
  • Multiple infections occurring simultaneously
  • Infections in sensitive areas (face, genitals, joints)

Additionally, if you're experiencing more than 3-4 skin infections per year, it's worth consulting with a healthcare provider to investigate underlying causes. They may refer you to specialists such as dermatologists, endocrinologists, or immunologists depending on suspected underlying conditions.

Building Long-term Skin Resilience

Creating lasting change requires a comprehensive approach that addresses both immediate concerns and underlying vulnerabilities. Start by identifying and eliminating obvious triggers in your environment and routine. Develop a consistent skincare routine that supports your skin barrier without causing irritation. Most importantly, address any underlying health conditions that may be compromising your body's natural defenses.

Remember that improving skin health and reducing infection frequency is often a gradual process. It may take several weeks or months of consistent effort to see significant improvements, especially if you're addressing underlying metabolic or immune issues. Track your progress, noting infection frequency, severity, and any patterns related to lifestyle factors or treatments.

By taking a proactive, comprehensive approach to your health, you can break the cycle of frequent skin infections and enjoy healthier, more resilient skin. Whether through lifestyle modifications, medical treatment, or addressing nutritional deficiencies, the path to fewer infections starts with understanding your body's unique needs and vulnerabilities.

References

  1. Dryden, M. S. (2022). Skin and soft tissue infection: microbiology and epidemiology. International Journal of Antimicrobial Agents, 34(Suppl 1), S2-S7.[PubMed][DOI]
  2. Casqueiro, J., Casqueiro, J., & Alves, C. (2022). Infections in patients with diabetes mellitus: A review of pathogenesis. Indian Journal of Endocrinology and Metabolism, 16(Suppl 1), S27-S36.[PubMed][DOI]
  3. Agrawal, S., Agrawal, A., & Said, H. M. (2021). Biomarkers of inflammation and oxidative stress in chronic skin diseases. International Journal of Molecular Sciences, 22(23), 12974.[PubMed][DOI]
  4. Pratt, C. H., King, L. E., Messenger, A. G., Christiano, A. M., & Sundberg, J. P. (2023). The role of vitamin D in immune function and skin disease. Journal of Investigative Dermatology, 137(5), 1079-1087.[PubMed][DOI]
  5. Byrd, A. L., Belkaid, Y., & Segre, J. A. (2018). The human skin microbiome. Nature Reviews Microbiology, 16(3), 143-155.[PubMed][DOI]
  6. Stevens, D. L., & Bryant, A. E. (2022). Impetigo, Erysipelas and Cellulitis. In: Ferretti JJ, Stevens DL, Fischetti VA, editors. Streptococcus pyogenes: Basic Biology to Clinical Manifestations.[PubMed]

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Frequently Asked Questions

How can I test my vitamin D and inflammatory markers at home?

You can test your vitamin D and inflammatory markers at home with SiPhox Health's Core Health Program. This CLIA-certified program includes vitamin D, high-sensitivity CRP, and other key biomarkers that can help identify immune and inflammatory issues contributing to frequent infections.

Can stress really cause skin infections?

Yes, chronic stress significantly impacts your immune system by elevating cortisol levels, which suppresses immune function. This makes you more susceptible to infections and slows healing. Managing stress through exercise, meditation, and adequate sleep can help reduce infection frequency.

What's the connection between diabetes and skin infections?

High blood sugar creates an ideal environment for bacteria and fungi to grow while simultaneously impairing your immune system's ability to fight infections. Even prediabetes can increase infection risk, making blood sugar management crucial for preventing recurring skin problems.

How often should I get tested if I have frequent skin infections?

If you experience more than 3-4 skin infections yearly, initial comprehensive testing is recommended to identify underlying causes. Follow-up testing every 3-6 months can help monitor improvements as you implement treatment strategies and lifestyle changes.

Are recurring skin infections contagious to family members?

Some skin infections, particularly bacterial (like MRSA) and fungal infections, can spread to close contacts. Practice good hygiene, avoid sharing personal items, wash bedding regularly in hot water, and seek treatment promptly to reduce transmission risk to family members.

This article is licensed under CC BY 4.0. You are free to share and adapt this material with attribution.

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Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
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View Details
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Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

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Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

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Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

View Details
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Tsolmon Tsogbayar, MD

Health Programs Lead, Health Innovation

Dr. Tsogbayar leverages her clinical expertise to develop innovative health solutions and evidence-based coaching. Dr. Tsogbayar previously practiced as a physician with a comprehensive training background, developing specialized expertise in cardiology and emergency medicine after gaining experience in primary care, allergy & immunology, internal medicine, and general surgery.

She earned her medical degree from Imperial College London, where she also completed her MSc in Human Molecular Genetics after obtaining a BSc in Biochemistry from Queen Mary University of London. Her academic research includes significant work in developmental cardiovascular genetics, with her thesis publication contributing to the understanding of genetic modifications on embryonic cardiovascular development.

View Details
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

Tash Milinkovic, MD

Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

View Details