Can exercise fix hormone problems?

Exercise can significantly improve many hormone imbalances by reducing cortisol, boosting testosterone and growth hormone, and enhancing insulin sensitivity. While it won't cure all hormonal conditions, regular physical activity is one of the most effective natural interventions for optimizing hormone health.

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The Exercise-Hormone Connection

Your hormones and exercise habits are deeply interconnected in ways that might surprise you. When you work out, your body doesn't just burn calories and build muscle - it triggers a complex cascade of hormonal responses that can either optimize or disrupt your endocrine system. The relationship works both ways: hormones influence your exercise performance and recovery, while physical activity directly impacts hormone production, sensitivity, and balance.

Research shows that regular exercise acts as a powerful hormone regulator, influencing everything from stress hormones like cortisol to reproductive hormones like testosterone and estrogen. In fact, studies indicate that consistent physical activity can improve insulin sensitivity by up to 50%, boost growth hormone production by 200-700% during intense exercise, and help normalize cortisol rhythms that affect sleep and stress response.

But here's what makes this particularly interesting: not all exercise affects hormones equally. The type, intensity, duration, and timing of your workouts all play crucial roles in determining whether exercise helps or hinders your hormonal health. Understanding these nuances can mean the difference between using exercise as medicine for hormone problems or inadvertently making imbalances worse.

Hormonal Response to Different Exercise Types

Individual responses vary based on fitness level, age, and baseline hormone status. Start conservatively and increase gradually.
Exercise TypePrimary Hormones AffectedPeak Response TimeOptimal Frequency
Resistance TrainingHeavy Resistance (70-85% 1RM)Testosterone, Growth Hormone, IGF-1Immediately post-workout3-4 times per week
Moderate CardioModerate Cardio (60-70% max HR)Insulin, Thyroid (T3/T4), CortisolDuring and 2-4 hours post150-300 min per week
HIITHigh-Intensity IntervalsGrowth Hormone, Testosterone, InsulinUp to 24 hours post1-2 times per week
Yoga/StretchingYoga/Mind-BodyCortisol (decreases), GABAImmediately and cumulativeDaily or 3-5 times per week

Individual responses vary based on fitness level, age, and baseline hormone status. Start conservatively and increase gradually.

Common Hormone Problems Exercise Can Address

Insulin Resistance and Blood Sugar Issues

Insulin resistance affects approximately 88% of American adults to some degree, making it one of the most common hormone-related health issues. Exercise is remarkably effective at improving insulin sensitivity through multiple mechanisms. During physical activity, your muscles can absorb glucose from the bloodstream without requiring insulin, providing an immediate blood sugar-lowering effect. Additionally, regular exercise increases the number and efficiency of insulin receptors on muscle cells, improving long-term glucose metabolism.

Both aerobic exercise and resistance training have proven benefits for insulin function. A 2013 study published in Diabetologia found that combining both types of exercise reduced HbA1c levels (a marker of long-term blood sugar control) more effectively than either type alone. Even a single bout of moderate exercise can improve insulin sensitivity for up to 48 hours afterward. If you're concerned about your metabolic health and insulin function, comprehensive testing can provide valuable insights into your glucose metabolism and help track improvements over time.

Cortisol Imbalances and Chronic Stress

Cortisol, your primary stress hormone, follows a natural daily rhythm - high in the morning to help you wake up, then gradually declining throughout the day. Chronic stress, poor sleep, and sedentary lifestyles can disrupt this pattern, leading to symptoms like fatigue, weight gain, anxiety, and sleep problems. Exercise acts as a controlled stressor that, when applied appropriately, helps recalibrate your stress response system.

Moderate-intensity exercise for 30-60 minutes has been shown to reduce overall cortisol levels and improve cortisol rhythm. However, timing matters: morning exercise can enhance the natural cortisol awakening response, while late-evening intense workouts might interfere with the normal nighttime cortisol decline and disrupt sleep. Yoga and tai chi have particularly strong evidence for normalizing cortisol patterns, with studies showing 23-31% reductions in cortisol levels after 12 weeks of practice.

Low Testosterone and Reproductive Hormones

Testosterone levels in men have declined by approximately 1% per year since the 1980s, with sedentary lifestyles being a major contributing factor. Exercise, particularly resistance training and high-intensity interval training (HIIT), can significantly boost testosterone production. A 2016 study found that men who performed regular strength training had 23% higher testosterone levels than sedentary controls.

For women, exercise helps balance reproductive hormones by reducing excess estrogen, improving progesterone production, and managing androgens. This is particularly beneficial for conditions like PCOS, where regular exercise can reduce testosterone levels by 25-30% and improve ovulation rates. The key is finding the right balance - excessive exercise can suppress reproductive hormones in both men and women, leading to conditions like hypothalamic amenorrhea in females and exercise-induced hypogonadism in males.

Understanding your baseline hormone levels through comprehensive testing helps you track how exercise interventions are affecting your hormonal health and adjust your routine accordingly.

How Different Types of Exercise Impact Hormones

Resistance Training: The Hormone Optimizer

Resistance training stands out as one of the most effective exercise modalities for hormone optimization. Heavy compound movements like squats, deadlifts, and bench presses trigger significant increases in growth hormone and testosterone. The hormonal response is most pronounced when using weights at 70-85% of your one-rep maximum, with rest periods of 60-90 seconds between sets. This creates the metabolic stress necessary for hormone release while avoiding the excessive cortisol response that comes with very high-intensity training.

Studies show that resistance training can increase growth hormone levels by up to 700% immediately post-workout, with elevated levels persisting for several hours. This growth hormone pulse promotes muscle growth, fat burning, and cellular repair. For optimal hormonal benefits, aim for 3-4 resistance training sessions per week, focusing on multi-joint exercises that engage large muscle groups.

Cardiovascular Exercise: The Metabolic Regulator

Aerobic exercise excels at improving insulin sensitivity and thyroid function. Moderate-intensity cardio (60-70% max heart rate) for 30-45 minutes enhances insulin receptor sensitivity and increases the conversion of T4 to the active T3 thyroid hormone. This type of exercise also stimulates the production of irisin, a hormone that helps convert white fat to metabolically active brown fat, improving overall metabolic health.

However, excessive cardio can backfire hormonally. Running more than 40 miles per week or engaging in daily high-intensity cardio sessions can suppress testosterone, elevate cortisol chronically, and reduce thyroid hormone production. The sweet spot for most people is 150-300 minutes of moderate-intensity cardio per week, spread across 3-5 sessions.

HIIT: The Efficiency Expert

High-intensity interval training offers unique hormonal benefits in a time-efficient package. HIIT sessions lasting just 15-20 minutes can boost growth hormone production for up to 24 hours post-exercise. This exercise style also improves mitochondrial function, which is crucial for hormone production since many hormones are synthesized in the mitochondria. Research shows that 12 weeks of HIIT can improve insulin sensitivity by 35% and increase testosterone levels by 17% in men.

Exercise Strategies for Specific Hormone Conditions

PCOS Management Through Movement

For women with PCOS, exercise is particularly therapeutic. A combination of resistance training (2-3 times per week) and moderate cardio (150 minutes per week) can reduce insulin resistance by 30%, lower androgens by 25%, and improve ovulation rates by 50%. The key is consistency rather than intensity - studies show that moderate, regular exercise is more beneficial than sporadic high-intensity workouts for PCOS management.

Thyroid Dysfunction and Exercise

Exercise affects thyroid hormones in complex ways. For those with hypothyroidism, regular moderate exercise can improve T4 to T3 conversion and enhance cellular sensitivity to thyroid hormones. However, excessive exercise can suppress TSH and reduce thyroid hormone production, particularly in those already dealing with thyroid issues. The recommendation is to start with low-impact activities like walking, swimming, or yoga, gradually increasing intensity as thyroid function improves.

If you have thyroid concerns, it's important to monitor not just TSH but also Free T3, Free T4, and thyroid antibodies to get a complete picture of thyroid function. Regular testing helps ensure your exercise routine is supporting rather than suppressing thyroid health.

Adrenal Fatigue Recovery Protocol

While 'adrenal fatigue' isn't a recognized medical diagnosis, many people experience symptoms of HPA (hypothalamic-pituitary-adrenal) axis dysfunction. For these individuals, gentle exercise is key. Start with restorative practices like walking, gentle yoga, or swimming for 20-30 minutes daily. Avoid high-intensity exercise until cortisol patterns normalize, as intense workouts can further stress an already taxed system. As recovery progresses, gradually introduce strength training with longer rest periods and moderate cardio.

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When Exercise Alone Isn't Enough

While exercise is a powerful tool for hormone optimization, it's important to recognize its limitations. Certain hormonal conditions require medical intervention alongside lifestyle modifications. For example, Type 1 diabetes, primary hypogonadism, Hashimoto's thyroiditis, and Addison's disease all require hormone replacement therapy that exercise cannot substitute for.

Additionally, the effectiveness of exercise for hormone balance depends on other lifestyle factors. Poor sleep (less than 7 hours nightly) can negate the hormonal benefits of exercise by elevating cortisol and suppressing testosterone and growth hormone. Similarly, a diet high in processed foods and sugar can maintain insulin resistance despite regular exercise. Chronic stress from work or relationships can keep cortisol elevated even with a perfect workout routine.

This is why a comprehensive approach is essential. Exercise works best for hormone optimization when combined with adequate sleep (7-9 hours), stress management techniques, a nutrient-dense diet, and appropriate medical care when needed. Some signs that you need medical evaluation include: persistent fatigue despite regular exercise, inability to lose weight with diet and exercise, irregular menstrual cycles, severe mood changes, or symptoms that worsen with exercise.

Creating Your Hormone-Optimizing Exercise Plan

Designing an exercise program for hormone optimization requires personalization based on your current hormone status, fitness level, and health goals. Start by establishing a baseline through comprehensive hormone testing, then build your program gradually. Here's a framework to get started:

  • Week 1-4: Focus on establishing consistency with 3-4 days of moderate exercise (walking, light resistance training, yoga)
  • Week 5-8: Introduce more structured resistance training 2-3 times per week, maintaining 2 days of cardio
  • Week 9-12: Add one HIIT session per week if recovery is good, optimize workout timing based on energy levels
  • Beyond 12 weeks: Fine-tune based on hormone test results and symptom improvements

Pay attention to recovery signals like sleep quality, morning energy levels, and workout performance. If you notice declining performance, increased fatigue, or mood changes, you may be overtraining and need to reduce intensity or volume. Remember that hormone optimization is a marathon, not a sprint - consistency over months and years yields the best results.

For those looking to understand their current hormone status and track improvements, consider getting comprehensive hormone testing every 3-6 months. This allows you to see objective changes in markers like testosterone, cortisol, thyroid hormones, and insulin sensitivity, helping you adjust your exercise program for optimal results. You can also upload your existing blood test results for a free analysis to understand your baseline hormone levels before starting your exercise program.

The Bottom Line: Exercise as Hormone Medicine

Exercise is one of the most powerful tools available for naturally optimizing hormone health. From improving insulin sensitivity and balancing cortisol to boosting testosterone and supporting thyroid function, regular physical activity influences virtually every aspect of your endocrine system. The key is finding the right type, intensity, and frequency of exercise for your individual needs and hormone status.

While exercise can significantly improve many hormone imbalances, it works best as part of a comprehensive approach that includes proper nutrition, adequate sleep, stress management, and medical care when needed. Start slowly, be consistent, monitor your progress through both symptoms and objective testing, and adjust your approach based on how your body responds. With patience and the right strategy, exercise can indeed help fix many hormone problems and optimize your overall health and vitality.

References

  1. Hackney, A. C., & Lane, A. R. (2015). Exercise and the Regulation of Endocrine Hormones. Progress in Molecular Biology and Translational Science, 135, 293-311.[PubMed][DOI]
  2. Vaamonde, D., Da Silva-Grigoletto, M. E., García-Manso, J. M., Barrera, N., & Vaamonde-Lemos, R. (2012). Physically active men show better semen parameters and hormone values than sedentary men. European Journal of Applied Physiology, 112(9), 3267-3273.[PubMed][DOI]
  3. Bird, S. R., & Hawley, J. A. (2017). Update on the effects of physical activity on insulin sensitivity in humans. BMJ Open Sport & Exercise Medicine, 2(1), e000143.[PubMed][DOI]
  4. Kraemer, W. J., & Ratamess, N. A. (2005). Hormonal responses and adaptations to resistance exercise and training. Sports Medicine, 35(4), 339-361.[PubMed][DOI]
  5. Harrison, C. L., Lombard, C. B., Moran, L. J., & Teede, H. J. (2011). Exercise therapy in polycystic ovary syndrome: a systematic review. Human Reproduction Update, 17(2), 171-183.[PubMed][DOI]
  6. Ciloglu, F., Peker, I., Pehlivan, A., Karacabey, K., Ilhan, N., Saygin, O., & Ozmerdivenli, R. (2005). Exercise intensity and its effects on thyroid hormones. Neuroendocrinology Letters, 26(6), 830-834.[PubMed]

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Frequently Asked Questions

How can I test my hormones at home?

You can test your hormones at home with SiPhox Health's Hormone Focus Program, which includes comprehensive testing of key hormones including testosterone, cortisol, DHEA-S, and sex hormone markers, providing lab-quality results from the comfort of your home.

How long does it take for exercise to improve hormone levels?

Initial improvements in insulin sensitivity can occur within 48 hours of a single workout. For hormones like testosterone and cortisol, significant changes typically appear after 6-12 weeks of consistent exercise. Growth hormone responds immediately to exercise but long-term adaptations develop over 8-12 weeks.

Can too much exercise make hormone problems worse?

Yes, overtraining can suppress testosterone, thyroid hormones, and reproductive hormones while chronically elevating cortisol. Signs of overtraining include persistent fatigue, declining performance, mood changes, and disrupted sleep. Most people should limit intense exercise to 4-5 days per week with adequate recovery.

What's the best type of exercise for balancing hormones?

A combination of resistance training (2-3 times per week) and moderate cardio (150 minutes per week) provides optimal hormone benefits. Resistance training boosts testosterone and growth hormone, while cardio improves insulin sensitivity and thyroid function. Add one HIIT session weekly for additional metabolic benefits.

Should I exercise differently during different phases of my menstrual cycle?

Yes, adapting exercise to your cycle can optimize results. During the follicular phase (days 1-14), you can handle higher intensity workouts. During the luteal phase (days 15-28), focus on moderate intensity exercise as cortisol sensitivity increases. During menstruation, gentle movement like yoga or walking may feel best.

This article is licensed under CC BY 4.0. You are free to share and adapt this material with attribution.

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Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

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His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

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Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

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Health Programs Lead, Health Innovation

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View Details
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Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

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Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
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His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

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In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
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Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

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View Details
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Tsolmon Tsogbayar, MD

Health Programs Lead, Health Innovation

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She earned her medical degree from Imperial College London, where she also completed her MSc in Human Molecular Genetics after obtaining a BSc in Biochemistry from Queen Mary University of London. Her academic research includes significant work in developmental cardiovascular genetics, with her thesis publication contributing to the understanding of genetic modifications on embryonic cardiovascular development.

View Details
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

Tash Milinkovic, MD

Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

View Details
Tsolmon Tsogbayar, MD

Tsolmon Tsogbayar, MD

Health Programs Lead, Health Innovation

Dr. Tsogbayar leverages her clinical expertise to develop innovative health solutions and evidence-based coaching. Dr. Tsogbayar previously practiced as a physician with a comprehensive training background, developing specialized expertise in cardiology and emergency medicine after gaining experience in primary care, allergy & immunology, internal medicine, and general surgery.

She earned her medical degree from Imperial College London, where she also completed her MSc in Human Molecular Genetics after obtaining a BSc in Biochemistry from Queen Mary University of London. Her academic research includes significant work in developmental cardiovascular genetics, with her thesis publication contributing to the understanding of genetic modifications on embryonic cardiovascular development.

View Details
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

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Tash Milinkovic, MD

Tash Milinkovic, MD

Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

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