Why am I gaining weight like a man?

Women who gain weight in a "male pattern" (around the midsection) often have hormonal imbalances like high testosterone, insulin resistance, or PCOS. Understanding these hormonal drivers through comprehensive testing can help identify the root cause and guide targeted treatment strategies.

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Understanding Male-Pattern Weight Gain in Women

If you've noticed that you're gaining weight primarily around your midsection, developing a thicker waist, or accumulating fat in your upper body rather than your hips and thighs, you might be experiencing what's commonly called "male-pattern" weight gain. This type of weight distribution, technically known as android or central obesity, can be particularly frustrating for women who expect to gain weight in more traditionally feminine patterns.

The difference between male and female weight gain patterns isn't just cosmetic. Where your body stores fat can provide important clues about your hormonal health and metabolic function. Women typically store fat in a gynoid pattern (hips, thighs, and buttocks), while men tend toward android patterns (abdomen and upper body). When women start gaining weight like men, it often signals an underlying hormonal imbalance that needs attention.

Understanding why this shift happens requires looking at the complex interplay between hormones like testosterone, estrogen, insulin, and cortisol. These hormones don't just influence where you store fat; they also affect your metabolism, appetite, muscle mass, and overall body composition. Getting to the root cause through comprehensive hormone testing can help you develop a targeted approach to managing your weight and overall health.

Male vs Female Fat Distribution Patterns

Fat distribution patterns provide important clues about hormonal health and metabolic function.
CharacteristicFemale Pattern (Gynoid)Male Pattern (Android)Health Implications
Primary Storage AreasPrimary Storage AreasHips, thighs, buttocksAbdomen, upper bodyAndroid pattern increases disease risk
Fat TypeFat TypeMostly subcutaneousMore visceral fatVisceral fat is metabolically active
Hormonal DriverHormonal DriverEstrogen dominantTestosterone/androgensHormone imbalance affects distribution
Metabolic ImpactMetabolic ImpactLower insulin resistanceHigher insulin resistanceAndroid pattern worsens metabolism

Fat distribution patterns provide important clues about hormonal health and metabolic function.

The Science Behind Gender-Specific Fat Distribution

Fat distribution patterns are primarily controlled by sex hormones, with estrogen promoting lower body fat storage and testosterone favoring abdominal fat accumulation. In premenopausal women, estrogen directs fat storage to the hips and thighs, creating the characteristic pear-shaped body type. This pattern isn't just aesthetic; subcutaneous fat in these areas is metabolically safer than visceral fat around organs.

When hormone balance shifts, so does fat distribution. Research shows that women with higher testosterone levels tend to accumulate more visceral fat, the type of fat that surrounds internal organs and increases health risks. This visceral fat is metabolically active, releasing inflammatory compounds and affecting insulin sensitivity, creating a cycle that can make weight loss increasingly difficult.

The Role of Adipose Tissue

Adipose tissue itself acts as an endocrine organ, producing hormones and inflammatory markers that influence metabolism. Visceral fat cells are particularly problematic because they're more metabolically active than subcutaneous fat cells. They release more free fatty acids, inflammatory cytokines, and hormones that can disrupt insulin signaling and promote further weight gain.

Additionally, fat cells contain an enzyme called aromatase that converts testosterone to estrogen. In women with excess abdominal fat, this conversion process can become dysregulated, potentially leading to a relative increase in testosterone activity despite normal or even elevated estrogen levels. Understanding these complex interactions helps explain why male-pattern weight gain often becomes self-perpetuating.

Common Hormonal Culprits

Elevated Testosterone and Androgens

High testosterone levels in women can directly promote abdominal fat storage while simultaneously making it harder to lose weight. Even slight elevations in testosterone or other androgens like DHEA-S can shift fat distribution patterns. Women with elevated androgens often notice increased belly fat, difficulty losing weight despite diet and exercise, and may also experience other symptoms like acne, hair loss, or excessive hair growth.

Free testosterone, the unbound form that's biologically active, is particularly important to measure. Total testosterone might appear normal while free testosterone is elevated due to low levels of sex hormone-binding globulin (SHBG). This is why comprehensive hormone panels that include SHBG, free testosterone calculations, and other androgens provide a more complete picture than testing testosterone alone.

Insulin Resistance and Metabolic Dysfunction

Insulin resistance is both a cause and consequence of male-pattern weight gain in women. When cells become resistant to insulin's effects, the pancreas produces more insulin to compensate. High insulin levels promote fat storage, particularly in the abdominal area, and make it extremely difficult to burn fat for energy. Insulin resistance also stimulates the ovaries to produce more testosterone, creating a vicious cycle.

Markers of insulin resistance include elevated fasting insulin, high HbA1c, elevated triglycerides, and low HDL cholesterol. The triglyceride to HDL ratio is a particularly useful marker that can indicate insulin resistance even when glucose levels appear normal. Women with insulin resistance often experience intense carbohydrate cravings, energy crashes after meals, and difficulty losing weight even with caloric restriction.

Chronic stress and elevated cortisol levels strongly promote abdominal fat storage. Cortisol mobilizes glucose for the fight-or-flight response, but when stress is chronic, this leads to consistently elevated blood sugar and insulin levels. High cortisol also breaks down muscle tissue, lowering metabolic rate, and can interfere with thyroid hormone function, further slowing metabolism.

The timing of cortisol release matters too. Cortisol should be highest in the morning and gradually decline throughout the day. Disrupted cortisol rhythms, where levels remain elevated at night or don't rise properly in the morning, can affect sleep quality, appetite regulation, and fat storage patterns. Testing cortisol at multiple points throughout the day provides insight into your stress response and circadian rhythm.

PCOS: A Major Driver of Male-Pattern Weight Gain

Polycystic ovary syndrome (PCOS) affects up to 10% of women of reproductive age and is one of the most common causes of male-pattern weight gain in women. PCOS is characterized by elevated androgens, insulin resistance, and often (but not always) polycystic ovaries. About 50-70% of women with PCOS struggle with weight gain, particularly around the midsection.

PCOS creates a perfect storm for abdominal weight gain through multiple mechanisms. High insulin levels stimulate the ovaries to produce excess testosterone. The elevated androgens promote visceral fat accumulation, which worsens insulin resistance. This creates a self-perpetuating cycle that makes weight loss extremely challenging without addressing the underlying hormonal imbalances.

Diagnosing PCOS requires ruling out other conditions and typically involves finding two of three criteria: irregular periods, clinical or biochemical signs of high androgens, and polycystic ovaries on ultrasound. However, many women with PCOS have normal-appearing ovaries, making blood tests for hormones like testosterone, DHEA-S, LH, FSH, and metabolic markers crucial for diagnosis.

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Other Medical Conditions to Consider

Thyroid Dysfunction

Hypothyroidism can contribute to weight gain and changes in body composition. While thyroid-related weight gain is often more generalized than specifically male-pattern, low thyroid function can worsen insulin resistance and affect sex hormone balance. Subclinical hypothyroidism, where TSH is elevated but free T4 remains normal, can still impact metabolism and make weight loss difficult.

The relationship between thyroid function and weight is complex. Low thyroid hormone reduces metabolic rate, decreases thermogenesis, and can lead to water retention. It also affects the production and clearance of sex hormones, potentially contributing to relative androgen excess. Comprehensive thyroid testing including TSH, free T3, free T4, and thyroid antibodies can identify subtle thyroid issues that might be contributing to weight gain.

Cushing's Syndrome

Though rare, Cushing's syndrome causes distinctive central weight gain with fat accumulation in the abdomen, face, and upper back. This condition results from prolonged exposure to high cortisol levels, either from overproduction by the adrenal glands or long-term corticosteroid medication use. Women with Cushing's often develop purple stretch marks, easy bruising, and muscle weakness along with central obesity.

Menopause and Perimenopause

The menopausal transition naturally shifts fat distribution from hips and thighs to the abdomen. As estrogen levels decline, the protective effect against visceral fat accumulation is lost. Many women notice their body shape changing even without significant weight gain, as fat redistributes from lower body to midsection. Perimenopause can be particularly challenging as hormone levels fluctuate unpredictably, affecting metabolism, appetite, and fat storage.

Testing and Diagnosis Strategies

Identifying the root cause of male-pattern weight gain requires comprehensive testing beyond basic metabolic panels. A thorough hormonal evaluation should include sex hormones (testosterone, free testosterone, estradiol, SHBG, DHEA-S), metabolic markers (fasting glucose, insulin, HbA1c, lipid panel), thyroid function (TSH, free T3, free T4), and stress hormones (cortisol at multiple time points).

For women with suspected PCOS, additional tests might include LH and FSH (looking for an elevated LH:FSH ratio), anti-Müllerian hormone (often elevated in PCOS), and sometimes a glucose tolerance test with insulin measurements. Inflammatory markers like high-sensitivity CRP can also provide valuable information about metabolic health and cardiovascular risk.

Timing of testing matters for accurate results. Hormones should ideally be tested at specific points in the menstrual cycle for premenopausal women. Day 3 testing captures baseline hormone levels, while day 21 testing can assess progesterone and confirm ovulation. For women with irregular cycles or those in perimenopause, testing may need to be repeated or timed differently. Regular monitoring through at-home testing programs can help track hormone changes over time and assess treatment effectiveness.

If you already have recent blood work, you can get a comprehensive analysis of your results using SiPhox Health's free upload service. This service provides personalized insights into your hormone levels, metabolic markers, and other biomarkers that might be contributing to your weight gain patterns.

Treatment Approaches and Lifestyle Modifications

Dietary Strategies

For women with male-pattern weight gain, particularly those with insulin resistance or PCOS, a lower-carbohydrate approach often works better than traditional low-fat diets. Reducing refined carbohydrates and sugars helps lower insulin levels, which can improve both weight loss and hormone balance. Focus on whole foods, adequate protein (at least 0.8-1g per pound of ideal body weight), healthy fats, and fiber-rich vegetables.

Meal timing and composition matter too. Eating protein and vegetables before carbohydrates can blunt glucose and insulin spikes. Some women benefit from intermittent fasting or time-restricted eating, which can improve insulin sensitivity and promote fat loss. However, very low-calorie diets or excessive fasting can backfire by increasing cortisol and disrupting thyroid function.

Exercise Recommendations

Resistance training is particularly beneficial for women with male-pattern weight gain. Building muscle improves insulin sensitivity, increases metabolic rate, and helps counteract the muscle loss associated with high cortisol. Aim for 2-3 strength training sessions per week focusing on compound movements that work multiple muscle groups.

While cardio has benefits, excessive high-intensity cardio can increase cortisol and may worsen hormonal imbalances. Instead, combine moderate cardio with strength training and stress-reducing activities like yoga or walking. High-intensity interval training (HIIT) can be effective but should be limited to 1-2 sessions per week to avoid overtaxing the stress response system.

Stress Management and Sleep

Since chronic stress and poor sleep directly contribute to abdominal weight gain, addressing these factors is crucial. Aim for 7-9 hours of quality sleep nightly, maintaining consistent sleep and wake times. Create a relaxing bedtime routine, limit screen time before bed, and keep your bedroom cool and dark.

Incorporate daily stress management practices such as meditation, deep breathing exercises, or gentle yoga. Even 10 minutes of daily meditation can significantly impact cortisol levels. Consider adaptogenic herbs like ashwagandha or rhodiola, which may help modulate the stress response, though you should discuss supplements with your healthcare provider.

Medical Interventions and When to Seek Help

When lifestyle modifications aren't enough, medical interventions may be necessary. For women with PCOS, metformin can improve insulin sensitivity and may help with weight loss. Hormonal contraceptives can help regulate cycles and reduce androgen levels, though some formulations may worsen insulin resistance. Anti-androgen medications like spironolactone can help with both hormonal symptoms and fluid retention.

For thyroid dysfunction, appropriate hormone replacement can restore metabolic function. Women in perimenopause or menopause might benefit from hormone replacement therapy, which can help maintain a more favorable body composition. However, hormone therapy requires careful consideration of individual risks and benefits.

Seek medical evaluation if you experience rapid weight gain (more than 5 pounds in a week), severe symptoms like excessive hair growth or loss, irregular periods lasting more than 35 days, or signs of severe insulin resistance such as dark, velvety skin patches (acanthosis nigricans). Early intervention can prevent progression to more serious conditions like type 2 diabetes or cardiovascular disease.

Taking Control of Your Health

Male-pattern weight gain in women is often a sign of underlying hormonal imbalances that extend beyond simple calories in versus calories out. Understanding the root cause through comprehensive testing allows for targeted interventions that address the hormonal drivers of weight gain, not just the symptoms. This approach leads to more sustainable weight loss and improved overall health.

Remember that hormonal imbalances develop over time and often require patience to correct. Small, consistent changes in diet, exercise, stress management, and sleep can have profound effects on hormone balance and body composition. Track your progress not just through the scale but also through measurements, how your clothes fit, energy levels, and other symptoms.

Working with healthcare providers who understand the complexity of female hormones and metabolism is invaluable. Don't accept being told that your weight gain is simply due to aging or that you just need to eat less and exercise more. With the right testing, treatment approach, and support, you can address the underlying causes of male-pattern weight gain and achieve lasting improvements in both your weight and overall health.

References

  1. Pasquali, R., & Oriolo, C. (2019). Obesity and Androgens in Women. Frontiers of Hormone Research, 53, 120-134.[PubMed][DOI]
  2. Escobar-Morreale, H. F. (2018). Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment. Nature Reviews Endocrinology, 14(5), 270-284.[PubMed][DOI]
  3. Frank, A. P., de Souza Santos, R., Palmer, B. F., & Clegg, D. J. (2019). Determinants of body fat distribution in humans may provide insight about obesity-related health risks. Journal of Lipid Research, 60(10), 1710-1719.[PubMed][DOI]
  4. Santosa, S., & Jensen, M. D. (2015). Sex and sex steroids: impact on the kinetics of fatty acids underlying body shape. Hormone Molecular Biology and Clinical Investigation, 20(1), 15-23.[PubMed][DOI]
  5. Zore, T., Palafox, M., & Reue, K. (2018). Sex differences in obesity, lipid metabolism, and inflammation—A role for the sex chromosomes? Molecular Metabolism, 15, 35-44.[PubMed][DOI]
  6. Teede, H. J., et al. (2018). Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Human Reproduction, 33(9), 1602-1618.[PubMed][DOI]

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Frequently Asked Questions

How can I test my hormones at home?

You can test your hormones at home with SiPhox Health's Hormone Focus Program. This CLIA-certified program includes comprehensive hormone testing including testosterone, DHEA-S, cortisol, and other key markers, providing lab-quality results from the comfort of your home.

What's the difference between male and female weight gain patterns?

Women typically gain weight in hips, thighs, and buttocks (gynoid pattern) due to estrogen's influence, while men gain weight around the midsection (android pattern) due to testosterone. When women develop male-pattern weight gain, it often indicates hormonal imbalances like elevated androgens or insulin resistance.

Can PCOS cause male-pattern weight gain?

Yes, PCOS is one of the most common causes of male-pattern weight gain in women. The condition causes elevated androgens and insulin resistance, both of which promote abdominal fat storage. About 50-70% of women with PCOS experience weight gain, particularly around the midsection.

How does insulin resistance affect where I store fat?

Insulin resistance promotes abdominal fat storage through multiple mechanisms. High insulin levels directly encourage fat storage in the midsection and stimulate the ovaries to produce more testosterone. This creates a cycle where abdominal fat worsens insulin resistance, making weight loss increasingly difficult.

What lifestyle changes help with hormone-related weight gain?

Focus on reducing refined carbohydrates to lower insulin levels, incorporate strength training to improve insulin sensitivity, manage stress through meditation or yoga, and prioritize 7-9 hours of quality sleep. These changes can help rebalance hormones and shift fat distribution patterns over time.

This article is licensed under CC BY 4.0. You are free to share and adapt this material with attribution.

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View Details
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Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
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Advisor

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View Details
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Advisor

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In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

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View Details
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Health Programs Lead, Health Innovation

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View Details
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Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

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Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

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Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

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Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

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Tash Milinkovic, MD

Tash Milinkovic, MD

Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

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