Why do I have fatty lumps in my skin?

Fatty lumps under the skin are usually lipomas—benign growths of fat cells that affect 1 in 1,000 people. While typically harmless, these soft, moveable lumps can be influenced by genetics, metabolic factors, and hormonal imbalances.

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What Are These Fatty Lumps Under Your Skin?

If you've noticed soft, doughy lumps beneath your skin that move slightly when pressed, you're likely dealing with lipomas—the most common type of benign soft tissue tumor. These fatty lumps affect approximately 1 in 1,000 people and are composed of mature fat cells enclosed in a thin, fibrous capsule. While they can appear anywhere on the body, they're most commonly found on the neck, shoulders, back, abdomen, arms, and thighs.

Lipomas typically feel soft and rubbery to the touch, are painless, and grow slowly over months or years. Most remain smaller than 2 inches in diameter, though some can grow larger. They're usually just beneath the skin (subcutaneous) but can occasionally develop deeper in muscle tissue. Understanding what causes these fatty deposits and when they might signal underlying health issues can help you make informed decisions about your health.

Common Types of Fatty Skin Lumps

Not all fatty lumps are created equal. While conventional lipomas are the most common, several variations exist, each with distinct characteristics. Understanding these differences can help you better communicate with your healthcare provider and determine the appropriate course of action.

Types of Fatty Lumps and Their Characteristics

Different types of fatty lumps have distinct characteristics that can help with diagnosis and treatment planning.
TypeTexturePain LevelCommon Location
Conventional LipomaConventional LipomaSoft, doughyUsually painlessNeck, shoulders, back, arms
AngiolipomaAngiolipomaSlightly firmOften tender/painfulForearms, trunk
FibrolipomaFibrolipomaFirm, rubberyGenerally painlessBack, neck, shoulders
Spindle Cell LipomaSpindle Cell LipomaFirmPainlessNeck, shoulders (men)

Different types of fatty lumps have distinct characteristics that can help with diagnosis and treatment planning.

Conventional Lipomas

These are the standard fatty lumps most people encounter. They contain mature white fat cells and typically appear as single, isolated growths. Conventional lipomas are soft, mobile, and grow slowly over time. They're usually painless unless they press against nerves or contain blood vessels.

Angiolipomas

Unlike conventional lipomas, angiolipomas contain blood vessels along with fat tissue. They tend to be more painful or tender to the touch and often appear in younger adults. Multiple angiolipomas frequently develop on the forearms, and they may have a slightly firmer texture than regular lipomas.

Fibrolipomas and Spindle Cell Lipomas

Fibrolipomas contain both fat and fibrous tissue, making them feel firmer than conventional lipomas. Spindle cell lipomas, typically found on the neck and shoulders of middle-aged men, contain spindle-shaped cells along with fat cells. Both types are benign but may require different treatment approaches due to their composition.

What Causes Fatty Lumps to Form?

The exact cause of lipomas remains somewhat mysterious, but research has identified several contributing factors. Understanding these can help you assess your risk and potentially identify underlying health conditions that may need attention.

Genetic and Hereditary Factors

Genetics play a significant role in lipoma development. If your parents or siblings have lipomas, you're more likely to develop them too. Some families carry specific genetic mutations that predispose them to multiple lipomas. Conditions like familial multiple lipomatosis can cause dozens or even hundreds of lipomas to form throughout the body. Research suggests that chromosomal abnormalities, particularly involving chromosome 12, may contribute to lipoma formation.

Metabolic and Hormonal Influences

Your metabolic health significantly impacts fatty tissue regulation. Insulin resistance, often seen in prediabetes and metabolic syndrome, can affect how your body stores and processes fat, potentially contributing to lipoma formation. Hormonal imbalances, particularly involving growth hormone, cortisol, and sex hormones, may also play a role. If you're concerned about metabolic factors contributing to fatty lumps, comprehensive metabolic testing can provide valuable insights into your glucose regulation, insulin sensitivity, and lipid metabolism.

Trauma and Injury

Some lipomas develop at sites of previous trauma or injury, leading to the term 'post-traumatic lipomas.' While the exact mechanism isn't fully understood, researchers believe that trauma may trigger abnormal fat cell proliferation during the healing process. This connection suggests that the body's repair mechanisms might sometimes go awry, leading to benign tumor formation.

Medical Conditions Associated with Multiple Lipomas

While isolated lipomas are usually harmless, multiple lipomas can sometimes indicate underlying medical conditions. Recognizing these associations helps ensure proper diagnosis and treatment.

  • Dercum's Disease (Adiposis Dolorosa): Characterized by multiple painful lipomas, often accompanied by obesity, fatigue, and mental disturbances
  • Madelung's Disease: Causes symmetric lipomas around the neck and shoulders, often associated with alcohol use disorder
  • Gardner Syndrome: A genetic condition causing intestinal polyps, bone tumors, and multiple lipomas
  • Multiple Endocrine Neoplasia (MEN) Syndrome: Can cause lipomas along with tumors in endocrine glands
  • Cowden Syndrome: Increases risk of various benign growths including lipomas and certain cancers

These conditions often involve metabolic, hormonal, or genetic abnormalities that affect multiple body systems. If you have multiple lipomas or a family history of these conditions, discussing comprehensive health screening with your healthcare provider is important.

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When Should You Worry About Fatty Lumps?

Most lipomas are benign and don't require treatment unless they cause discomfort or cosmetic concerns. However, certain warning signs warrant immediate medical attention to rule out liposarcoma, a rare cancerous tumor that can mimic lipomas.

Red Flag Symptoms

  • Rapid growth over weeks or months
  • Size larger than 5 centimeters (2 inches)
  • Deep location within muscle tissue
  • Firm or hard texture rather than soft and doughy
  • Fixed position (doesn't move when pressed)
  • Pain or tenderness that worsens over time
  • Skin changes over the lump
  • Return of a lump after previous removal

Additionally, if you develop multiple lipomas suddenly or notice other systemic symptoms like unexplained weight loss, fatigue, or night sweats, seek medical evaluation promptly. These could indicate underlying conditions requiring treatment.

Diagnosis and Medical Evaluation

Diagnosing lipomas typically begins with a physical examination. Your doctor will feel the lump, noting its size, texture, mobility, and location. In many cases, experienced physicians can diagnose lipomas through physical examination alone.

Imaging and Biopsy

When the diagnosis is uncertain or the lump has concerning features, additional tests may be necessary:

  • Ultrasound: Shows the lump's composition and blood flow patterns
  • MRI or CT scan: Provides detailed images for deeper or larger lumps
  • Fine needle aspiration: Removes cells for microscopic examination
  • Excisional biopsy: Removes the entire lump for comprehensive analysis

Your doctor might also recommend blood tests to check for metabolic abnormalities, especially if you have multiple lipomas or other symptoms suggesting an underlying condition.

Treatment Options for Fatty Lumps

Treatment for lipomas depends on their size, location, symptoms, and your personal preferences. Many people choose to leave asymptomatic lipomas alone, while others opt for removal due to discomfort or cosmetic concerns.

Surgical Removal

Surgical excision remains the most definitive treatment for lipomas. The procedure involves making an incision over the lump and removing it along with its capsule. This outpatient procedure typically takes 30-60 minutes under local anesthesia. Complete removal of the capsule minimizes recurrence risk to less than 5%. Recovery usually involves minimal downtime, though larger lipomas may require more extensive surgery and longer healing times.

Minimally Invasive Options

For those seeking less invasive alternatives, several options exist:

  • Liposuction: Removes the fatty content through a small incision but may leave the capsule behind
  • Steroid injections: Can shrink lipomas by breaking down fat cells, though complete resolution is rare
  • Laser therapy: Uses focused light energy to destroy fat cells with minimal scarring

These treatments may have higher recurrence rates than surgical excision but offer benefits like smaller scars and quicker recovery times.

The Role of Metabolic Health in Fatty Lump Prevention

While you can't always prevent lipomas, especially those with genetic causes, optimizing your metabolic health may reduce your risk and support overall well-being. Research suggests connections between metabolic dysfunction and abnormal fat tissue growth.

Key metabolic factors to monitor include insulin sensitivity, glucose regulation, lipid profiles, and inflammatory markers. Elevated insulin levels and insulin resistance can affect fat cell behavior and proliferation. Chronic inflammation, marked by elevated C-reactive protein (CRP) levels, may also contribute to abnormal tissue growth. Regular monitoring of these biomarkers through comprehensive metabolic testing can help you identify and address imbalances before they contribute to health issues.

Lifestyle Modifications

Supporting your metabolic health through lifestyle choices may help prevent some fatty lumps and improve overall health:

  • Maintain stable blood sugar through balanced nutrition and regular meal timing
  • Exercise regularly to improve insulin sensitivity and metabolic function
  • Manage stress through meditation, yoga, or other relaxation techniques
  • Ensure adequate sleep to support hormonal balance and metabolic regulation
  • Limit alcohol consumption, especially if you have multiple lipomas
  • Stay hydrated to support cellular function and waste removal

If you're interested in understanding your current metabolic health status and tracking improvements over time, consider uploading your existing blood test results for a comprehensive analysis at SiPhox Health's free upload service. This service can help you identify metabolic patterns that might contribute to fatty tissue abnormalities.

Living with Lipomas: Practical Considerations

For many people, lipomas are a minor cosmetic concern rather than a medical problem. However, their presence can affect quality of life, especially when they're visible or located in areas that interfere with clothing or movement.

Keep a record of your lipomas, noting their size, location, and any changes over time. This information helps your healthcare provider track progression and identify concerning changes. Photography can be particularly useful for monitoring subtle changes in size or appearance.

If you have multiple lipomas or a family history of lipoma-related conditions, consider genetic counseling. Understanding your genetic risk can inform screening recommendations for you and your family members. Some genetic conditions associated with lipomas also increase cancer risk, making early detection and monitoring crucial.

The Bottom Line on Fatty Skin Lumps

Fatty lumps under the skin are usually benign lipomas that pose no serious health threat. While their exact cause remains unclear, factors including genetics, metabolic health, hormonal balance, and previous trauma all play roles in their development. Most lipomas don't require treatment unless they cause discomfort or cosmetic concerns.

However, staying vigilant about changes in existing lumps and the development of new ones remains important. Warning signs like rapid growth, firmness, or pain warrant medical evaluation to rule out more serious conditions. By understanding the nature of these fatty lumps and maintaining optimal metabolic health, you can make informed decisions about when to seek treatment and how to support your overall well-being.

Remember that while lipomas themselves are rarely dangerous, they can sometimes signal underlying metabolic or genetic conditions that benefit from medical attention. Regular health monitoring, including metabolic biomarker testing, can help you maintain optimal health and catch potential issues early.

References

  1. Charifa A, Azmat CE, Badri T. Lipoma. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.[Link][PubMed]
  2. Kolb L, Yarrarapu SNS, Ameer MA, et al. Lipoma. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022.[Link][PubMed]
  3. Johnson CN, Ha AS, Chen E, Davidson D. Lipomatous Soft-tissue Tumors. J Am Acad Orthop Surg. 2018;26(22):779-788.[PubMed][DOI]
  4. Bancroft LW, Kransdorf MJ, Peterson JJ, O'Connor MI. Benign fatty tumors: classification, clinical course, imaging appearance, and treatment. Skeletal Radiol. 2006;35(10):719-733.[PubMed][DOI]
  5. Hansson E, Svensson H, Brorson H. Review of Dercum's disease and proposal of diagnostic criteria, diagnostic methods, classification and management. Orphanet J Rare Dis. 2012;7:23.[PubMed][DOI]
  6. Murphey MD, Carroll JF, Flemming DJ, Pope TL, Gannon FH, Kransdorf MJ. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics. 2004;24(5):1433-1466.[PubMed][DOI]

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Frequently Asked Questions

How can I test my metabolic health at home?

You can test your metabolic health at home with SiPhox Health's Heart & Metabolic Program, which includes comprehensive metabolic biomarkers like glucose, HbA1c, insulin sensitivity markers, and lipid profiles, providing lab-quality results from the comfort of your home.

Are fatty lumps under the skin cancerous?

The vast majority of fatty lumps (lipomas) are benign and non-cancerous. Less than 1% of soft tissue lumps are malignant. However, any lump that grows rapidly, is larger than 2 inches, feels firm or fixed, or causes pain should be evaluated by a healthcare provider to rule out liposarcoma or other serious conditions.

Can lipomas go away on their own?

Lipomas typically don't disappear on their own. Once formed, they usually remain stable or grow slowly over time. While some may shrink slightly with weight loss or metabolic improvements, complete spontaneous resolution is extremely rare. Treatment is necessary if you want to remove them completely.

What's the difference between a lipoma and a cyst?

Lipomas are solid masses of fat cells that feel soft and doughy, while cysts are fluid-filled sacs that may feel firmer or fluctuant. Lipomas typically move freely under the skin and grow slowly, while cysts may have a visible pore or punctum and can become infected or inflamed. A healthcare provider can usually distinguish between them through physical examination.

Can diet and exercise prevent lipomas?

While there's no guaranteed way to prevent lipomas, especially genetic ones, maintaining good metabolic health through balanced nutrition and regular exercise may help. Stable blood sugar, healthy insulin sensitivity, and reduced inflammation could potentially lower your risk, though more research is needed to establish direct causation.

This article is licensed under CC BY 4.0. You are free to share and adapt this material with attribution.

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Health Programs Lead, Health Innovation

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View Details
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Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

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Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

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Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

View Details
Tsolmon Tsogbayar, MD

Tsolmon Tsogbayar, MD

Health Programs Lead, Health Innovation

Dr. Tsogbayar leverages her clinical expertise to develop innovative health solutions and evidence-based coaching. Dr. Tsogbayar previously practiced as a physician with a comprehensive training background, developing specialized expertise in cardiology and emergency medicine after gaining experience in primary care, allergy & immunology, internal medicine, and general surgery.

She earned her medical degree from Imperial College London, where she also completed her MSc in Human Molecular Genetics after obtaining a BSc in Biochemistry from Queen Mary University of London. Her academic research includes significant work in developmental cardiovascular genetics, with her thesis publication contributing to the understanding of genetic modifications on embryonic cardiovascular development.

View Details
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

Tash Milinkovic, MD

Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

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