Why do I have nodules in my tendons?

Tendon nodules are small lumps that form due to repetitive strain, inflammatory conditions like rheumatoid arthritis, or metabolic disorders. They require proper diagnosis through physical examination and imaging, with treatment ranging from rest and physical therapy to medical interventions.

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Understanding Tendon Nodules

Tendon nodules are small, often palpable lumps that develop within or along the tendons, the fibrous connective tissues that attach muscles to bones. These nodules can range from barely noticeable bumps to larger masses that cause significant discomfort and functional limitations. While discovering a lump in your tendon can be concerning, understanding what causes these nodules and how they develop can help you make informed decisions about your health.

These nodules typically form as a result of the body's response to various stressors, including mechanical strain, inflammatory processes, or metabolic imbalances. They're most commonly found in tendons that experience frequent use or stress, such as those in the hands, feet, shoulders, and elbows. The development of tendon nodules often signals an underlying issue that needs attention, whether it's overuse, an inflammatory condition, or a systemic health problem.

Common Causes of Tendon Nodules

Repetitive Strain and Overuse

The most frequent cause of tendon nodules is repetitive strain injury (RSI). When tendons undergo repeated stress without adequate recovery time, the body responds by laying down extra collagen fibers in an attempt to strengthen the area. This process, while protective in intent, can lead to the formation of nodular thickenings. Athletes, musicians, and people whose jobs involve repetitive motions are particularly susceptible to developing these overuse-related nodules.

Common Causes of Tendon Nodules

Different causes require specific treatment approaches and monitoring strategies.
CauseTypical LocationKey FeaturesAssociated Conditions
Repetitive StrainRepetitive StrainHands, wrists, elbowsGradual onset, activity-related painTrigger finger, tennis elbow
Rheumatoid ArthritisRheumatoid ArthritisMultiple sites, symmetricalFirm nodules, morning stiffnessJoint deformities, systemic symptoms
GoutGoutFeet, hands, elbowsTophi (chalk-like deposits)Acute arthritis attacks, kidney stones
HyperlipidemiaHyperlipidemiaAchilles, hand extensorsYellowish xanthomasHigh cholesterol, heart disease risk

Different causes require specific treatment approaches and monitoring strategies.

Trigger finger, a condition where nodules form in the flexor tendons of the fingers, exemplifies this mechanism. The repeated gripping motions cause inflammation and scarring of the tendon sheath, eventually leading to nodule formation that can catch on the pulley system of the finger, causing the characteristic clicking or locking sensation.

Inflammatory and Autoimmune Conditions

Systemic inflammatory conditions represent another major category of causes for tendon nodules. Rheumatoid arthritis, for instance, can cause rheumatoid nodules to form in tendons and other soft tissues. These nodules result from immune-mediated inflammation that triggers abnormal tissue proliferation. Similarly, conditions like psoriatic arthritis and lupus can lead to inflammatory changes in tendons that manifest as nodular formations.

If you're experiencing tendon nodules along with joint pain, morning stiffness, or fatigue, it's important to get comprehensive testing to rule out autoimmune conditions. Regular monitoring of inflammatory markers like C-reactive protein (CRP) and rheumatoid factor can help track disease activity and guide treatment decisions.

Metabolic and Systemic Disorders

Metabolic disorders can also contribute to tendon nodule formation. Gout, characterized by elevated uric acid levels, can cause tophi (uric acid crystal deposits) to form in and around tendons. These gouty nodules are particularly common in the Achilles tendon and the tendons of the hands and feet. Diabetes mellitus is another metabolic condition associated with tendon problems, including nodule formation, due to the effects of chronic hyperglycemia on connective tissue.

Cholesterol deposits, known as xanthomas, can also form nodules in tendons, particularly in people with familial hypercholesterolemia or other lipid disorders. These yellowish nodules most commonly affect the Achilles tendons and the extensor tendons of the hands. Understanding these different causes is crucial for proper diagnosis and treatment.

Types and Locations of Tendon Nodules

Hand and Finger Nodules

The hands and fingers are common sites for tendon nodules due to their frequent use and complex tendon anatomy. Dupuytren's contracture causes nodules in the palmar fascia that can eventually affect the flexor tendons, leading to finger contractures. Giant cell tumors of the tendon sheath, despite their alarming name, are benign nodules that commonly occur in the fingers and hands. These lesions typically present as firm, slow-growing masses along the flexor tendon sheaths.

Lower Extremity Nodules

The Achilles tendon is particularly prone to nodule formation, especially in runners and other athletes. Achilles tendinopathy can lead to both insertional and mid-substance nodules that cause pain and stiffness. The patellar tendon, connecting the kneecap to the shinbone, can develop nodules in response to jumping activities, a condition sometimes called jumper's knee. Plantar fibromatosis causes nodules in the plantar fascia of the foot, which, while technically not a tendon, shares similar characteristics and treatment approaches.

Recognizing Symptoms and Warning Signs

Tendon nodules can present with various symptoms depending on their size, location, and underlying cause. The most obvious sign is a palpable lump along the course of a tendon. These lumps may be firm or rubbery to the touch and can be either mobile or fixed to surrounding tissues. Pain is common but not universal; some nodules are completely painless while others cause significant discomfort, especially with movement or pressure.

Functional limitations often accompany tendon nodules. You might notice decreased range of motion, weakness in the affected area, or difficulty performing specific movements. In the case of trigger finger, the nodule can cause catching or locking of the digit. Achilles tendon nodules may cause morning stiffness and pain with the first steps of the day. Some nodules may also cause visible swelling or changes in the contour of the affected area.

Red flag symptoms that warrant immediate medical attention include rapid growth of the nodule, severe pain, signs of infection (redness, warmth, fever), or any neurological symptoms like numbness or tingling. These could indicate more serious conditions requiring prompt evaluation and treatment.

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Diagnostic Approaches and Testing

Proper diagnosis of tendon nodules begins with a thorough medical history and physical examination. Your healthcare provider will ask about the onset of symptoms, any triggering activities, and associated symptoms. They'll examine the nodule, assessing its size, consistency, mobility, and relationship to surrounding structures. Special tests specific to the affected tendon may be performed to evaluate function and reproduce symptoms.

Imaging studies play a crucial role in diagnosis. Ultrasound is often the first-line imaging modality for tendon nodules, as it provides excellent visualization of soft tissue structures and can assess blood flow to the area. MRI offers more detailed images and can help differentiate between various types of nodules and assess the extent of tendon damage. X-rays, while not showing the nodules directly, can reveal calcifications or associated bone changes.

Laboratory testing may be necessary to identify underlying systemic conditions. Blood tests can check for inflammatory markers, autoimmune antibodies, uric acid levels, and metabolic parameters. If you're experiencing multiple tendon nodules or have other systemic symptoms, comprehensive biomarker testing can help identify underlying metabolic or inflammatory conditions that may be contributing to nodule formation.

In some cases, a biopsy may be recommended, especially if the diagnosis is uncertain or if there's concern about malignancy. While most tendon nodules are benign, certain characteristics may prompt further investigation to rule out rare conditions like sarcomas or other soft tissue tumors.

Treatment Options and Management Strategies

Conservative Management

Many tendon nodules respond well to conservative treatment approaches. Rest and activity modification are fundamental, allowing the affected tendon to heal while avoiding movements that exacerbate symptoms. Physical therapy plays a crucial role, incorporating stretching exercises, eccentric strengthening, and manual therapy techniques to improve tendon health and function. Ice application can help reduce inflammation and pain, particularly after activity.

Ergonomic modifications in the workplace or during sports activities can prevent further irritation. This might include using proper equipment, adjusting technique, or implementing regular breaks during repetitive activities. Splinting or bracing may be recommended to limit motion and allow healing, particularly for conditions like trigger finger or De Quervain's tenosynovitis.

Medical Interventions

When conservative measures fail, medical interventions may be necessary. Nonsteroidal anti-inflammatory drugs (NSAIDs) can help reduce pain and inflammation, though their long-term use should be monitored. Corticosteroid injections directly into or around the nodule can provide significant relief, particularly for inflammatory conditions, though repeated injections should be avoided due to the risk of tendon weakening.

For nodules caused by systemic conditions, treating the underlying disease is essential. This might involve disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis, uric acid-lowering medications for gout, or lipid-lowering therapy for cholesterol deposits. Newer treatments like platelet-rich plasma (PRP) injections and extracorporeal shock wave therapy show promise for certain types of tendon nodules, though more research is needed to establish their efficacy.

Surgical Considerations

Surgery is typically reserved for nodules that fail to respond to conservative treatment or cause significant functional impairment. Surgical options include nodule excision, tendon debridement, or release procedures for conditions like trigger finger. The specific approach depends on the location, size, and nature of the nodule, as well as the condition of the surrounding tendon.

Post-surgical rehabilitation is crucial for optimal outcomes. This typically involves a graduated program of range of motion exercises, strengthening, and functional training. Recovery time varies depending on the procedure and location but generally ranges from several weeks to several months.

Prevention and Long-term Management

Preventing tendon nodules involves addressing modifiable risk factors and maintaining overall tendon health. Proper warm-up before physical activity, gradual progression in training intensity, and adequate recovery between sessions can prevent overuse injuries. Maintaining good posture and ergonomics, especially during repetitive activities, reduces mechanical stress on tendons.

Regular stretching and strengthening exercises help maintain tendon flexibility and resilience. Cross-training and varying activities can prevent repetitive strain on specific tendons. Staying hydrated and maintaining a balanced diet rich in anti-inflammatory foods supports tendon health. Managing underlying health conditions through regular monitoring and appropriate treatment is essential for preventing nodule formation related to systemic diseases.

For those with chronic conditions that predispose to tendon nodules, regular follow-up with healthcare providers is important. This might include periodic imaging to monitor existing nodules, blood tests to track inflammatory markers or metabolic parameters, and adjustments to treatment plans based on disease activity. Early intervention when new nodules develop can prevent progression and maintain function.

If you're looking to better understand your metabolic and inflammatory health status, consider uploading your existing blood test results to SiPhox Health's free analysis service. This comprehensive analysis can help identify potential risk factors for tendon problems and provide personalized insights for optimizing your health.

Living with Tendon Nodules: Practical Tips

Living with tendon nodules requires adapting daily activities to minimize discomfort and prevent progression. Using assistive devices or adaptive equipment can help reduce strain on affected tendons during daily tasks. For hand nodules, ergonomic tools, jar openers, and modified grips can make activities easier. For lower extremity nodules, proper footwear with adequate support and cushioning is essential.

Pain management strategies beyond medication can be helpful. These include heat therapy before activity to improve flexibility, cold therapy after activity to reduce inflammation, and techniques like mindfulness and relaxation exercises to manage chronic pain. Some people find relief with complementary therapies like acupuncture or massage, though evidence for these approaches varies.

Maintaining a symptom diary can help identify triggers and track treatment effectiveness. Note activities that worsen symptoms, what provides relief, and any changes in the nodules over time. This information can be valuable for healthcare providers in adjusting treatment plans and can help you make informed decisions about activity modification.

References

  1. Abate, M., Schiavone, C., Salini, V., & Andia, I. (2013). Occurrence of tendon pathologies in metabolic disorders. Rheumatology, 52(4), 599-608.[Link][DOI]
  2. Kaux, J. F., Forthomme, B., Goff, C. L., Crielaard, J. M., & Croisier, J. L. (2011). Current opinions on tendinopathy. Journal of Sports Science & Medicine, 10(2), 238-253.[PubMed]
  3. Maffulli, N., Wong, J., & Almekinders, L. C. (2003). Types and epidemiology of tendinopathy. Clinics in Sports Medicine, 22(4), 675-692.[PubMed][DOI]
  4. Scott, A., Backman, L. J., & Speed, C. (2015). Tendinopathy: Update on pathophysiology. Journal of Orthopaedic & Sports Physical Therapy, 45(11), 833-841.[PubMed][DOI]
  5. Tilley, B. J., Cook, J. L., Docking, S. I., & Gaida, J. E. (2015). Is higher serum cholesterol associated with altered tendon structure or tendon pain? A systematic review. British Journal of Sports Medicine, 49(23), 1504-1509.[PubMed][DOI]
  6. Zayni, R., Thaunat, M., Fayard, J. M., et al. (2015). Platelet-rich plasma as a treatment for chronic patellar tendinopathy: comparison of a single versus two consecutive injections. Muscles, Ligaments and Tendons Journal, 5(2), 92-98.[PubMed]

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Frequently Asked Questions

How can I test my inflammatory markers at home?

You can test your inflammatory markers at home with SiPhox Health's Core Health Program, which includes high-sensitivity CRP testing along with other essential biomarkers. This CLIA-certified program provides lab-quality results from the comfort of your home.

Are tendon nodules cancerous?

The vast majority of tendon nodules are benign (non-cancerous). They typically result from inflammation, overuse, or systemic conditions like rheumatoid arthritis or gout. However, any rapidly growing, painful, or unusual nodule should be evaluated by a healthcare provider to rule out rare malignant conditions.

Can tendon nodules go away on their own?

Some tendon nodules can resolve with conservative treatment including rest, physical therapy, and addressing underlying causes. However, nodules caused by chronic conditions like Dupuytren's contracture or rheumatoid arthritis typically require ongoing management and may not completely disappear without medical intervention.

What's the difference between a tendon nodule and a ganglion cyst?

Tendon nodules are solid masses within or along the tendon made of fibrous tissue, while ganglion cysts are fluid-filled sacs that typically arise from joint capsules or tendon sheaths. Ganglion cysts are usually softer, may change in size, and can sometimes be transilluminated (light passes through them), whereas tendon nodules are firm and don't allow light to pass through.

When should I see a doctor about a tendon nodule?

You should see a doctor if the nodule is rapidly growing, causing severe pain, limiting your daily activities, or accompanied by systemic symptoms like fever, unexplained weight loss, or multiple nodules appearing simultaneously. Additionally, seek medical attention if you notice signs of infection or neurological symptoms like numbness or tingling.

This article is licensed under CC BY 4.0. You are free to share and adapt this material with attribution.

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Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
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Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

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Health Programs Lead, Health Innovation

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She earned her medical degree from Imperial College London, where she also completed her MSc in Human Molecular Genetics after obtaining a BSc in Biochemistry from Queen Mary University of London. Her academic research includes significant work in developmental cardiovascular genetics, with her thesis publication contributing to the understanding of genetic modifications on embryonic cardiovascular development.

View Details
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Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

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Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

View Details
Tsolmon Tsogbayar, MD

Tsolmon Tsogbayar, MD

Health Programs Lead, Health Innovation

Dr. Tsogbayar leverages her clinical expertise to develop innovative health solutions and evidence-based coaching. Dr. Tsogbayar previously practiced as a physician with a comprehensive training background, developing specialized expertise in cardiology and emergency medicine after gaining experience in primary care, allergy & immunology, internal medicine, and general surgery.

She earned her medical degree from Imperial College London, where she also completed her MSc in Human Molecular Genetics after obtaining a BSc in Biochemistry from Queen Mary University of London. Her academic research includes significant work in developmental cardiovascular genetics, with her thesis publication contributing to the understanding of genetic modifications on embryonic cardiovascular development.

View Details
Pavel Korecky, MD

Pavel Korecky, MD

Director of Clinical Product Operations

Director of Clinical Product Operations at SiPhox Health with a background in medicine and a passion for health optimization. Experienced in leading software and clinical development teams, contributing to patents, launching health-related products, and turning diagnostics into actionable tools.

View Details
Paul Thompson, MD

Paul Thompson, MD

Advisor

Paul D. Thompson is Chief of Cardiology Emeritus of Hartford Hospital and Professor Emeritus at University of Connecticut Medical School. He has authored over 500 scientific articles on cardiovascular risk factors, the effects of exercise, and beyond. He received National Institutes of Health’s (NIH) Preventive Cardiology Academic Award, and has received NIH funding for multiple studies.

Dr. Thompson’s interests in exercise, general cardiology and sports cardiology originated from his own distance running: he qualified for the 1972 Olympic Marathon Trials as a 3rd year medical student and finished 16th in the 1976 Boston Marathon. Dr. Thompson publishes a blog 500 Rules of Cardiology where he shares lessons and anecdotes that he has learned over his extensive career as a physician, researcher and teacher.

View Details
Robert Lufkin, MD

Robert Lufkin, MD

Advisor

Physician/medical school professor (UCLA and USC) and New York Times bestselling author empowering people to take back their metabolic health with lifestyle and other tools. A veteran of the Today Show, USA Today, and a regular contributor to FOX and other network news stations, his weekly video podcast reaches over 500,000 people. After reversing chronic disease and transforming his own life he is making it his mission to help others do the same.

His latest book, ‘Lies I Taught In Medical School’ is an instant New York Times bestseller and has re-framed how we think about metabolic health and longevity. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers and 14 books that are available in fourteen languages.

View Details
Ben Bikman, PhD

Ben Bikman, PhD

Advisor

Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

In addition to his academic pursuits, Dr. Bikman is the author of Why We Get Sick and How Not To Get Sick.

View Details
Tash Milinkovic, MD

Tash Milinkovic, MD

Health Programs Lead, Heart & Metabolic

Dr. Natasha Milinkovic is part of the clinical product team at SiPhox Health, having graduated from the University of Bristol Medical School. Her medical career includes rotations across medical and surgical specialties, with specialized research in vascular surgery, focusing on recovery and post-operative pain outcomes. Dr. Milinkovic built her expertise in emergency medicine as a clinical fellow at a major trauma center before practicing at a central London teaching hospital throughout the pandemic.

She has contributed to global health initiatives, implementing surgical safety standards and protocols across rural Uganda. Dr. Milinkovic initially joined SiPhox Health to spearhead the health coaching initiative and has been a key contributor in the development and launch of the Heart and Metabolic program. She is passionate about addressing health disparities by building scalable healthcare solutions.

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