ApoB

What is ApoB?

ApoB (apolipoprotein B) is an atherogenic (forms plaques in arteries) particle that transports "bad" cholesterol. Each particle of VLDL, IDL, LDL, or Lp(a) contains a single molecule of ApoB. Studies have shown that ApoB is a better predictor of cardiovascular events such as myocardial infarction than LDL-C in both men and women, independent of age.

Note: While VLDL, IDL, LDL, or Lp(a) particles in themselves are not "bad", high levels of these lipoproteins can build up and block arteries (pro-atherogenic). These lipoproteins, however, are healthy in moderation, and very low levels can have negative implications, too.

Why is it included in the Cardiovascular Axis?

Because there is only one ApoB per LDL particle, this measurement gives us the most accurate estimate of the quantity of non-HDL cholesterol relative to total cholesterol. High ApoB levels are strongly associated with increased risk for cardiovascular events and shortened lifespan. SiPhox Health offers ApoB as part of its at-home comprehensive test kits along with 16 other critical biomarkers.

How can I better understand my results?

To better interpret your results, here are a few values that can be used to gauge your cardiovascular health. It is important to consult with your physician if you are concerned with any of your results.

High ApoB results may be indicative of pregnancy, high cholesterol, or kidney issues. Low ApoB on the other hand may be indicative of sepsis, liver disease, malabsorption, or high estrogen levels.

If your ApoB levels are higher than normal, you can try:

Where can I learn more?

Peter Attia (podcast) - Dr. Dayspring: Lipid metrics, measurements, cholesterol regulation

NIH - Opening a New Lipid “Apo-thecary”

Cleveland Clinic - ApoB Test

 

DISCLAIMER: IF YOU ARE CONCERNED WITH ANY OF YOUR RESULTS, PLEASE CONSULT WITH YOUR PHYSICIAN.