Weight progress
Steady, healthy loss
-24 lb
From 240.7 lb to 216.5 lb - 3 months on therapy
STARTMONTH 1MONTH 2TODAY
HSA / FSA eligible
At-Home
GLP Optimization.
Fast. Painless.
Track what GLP therapy changes beyond weight40+ lab markersBody-composition trendsSymptom check-insNo lab visits
Start optimizing$199
+ Shipping & handling.
1M+Biomarkers tested
CLIA & CAPAccredited labs
If you're on GLP therapy, don't just track weight.
Track what appetite suppression and weight loss may be doing to your metabolism, heart health, hormones, nutrition, muscle, and overall health.
Useful before you start, while you are using GLP therapy, and as you taper off.
- 40+ direct and calculated lab markers across metabolism, lipids, liver, kidney, thyroid, hormones, nutrition, and inflammation
- In-app body-composition scanning to track fat loss vs muscle loss
- Symptom check-ins, insights, and actions built around your results
Tolerance scoreBaseline
How well your body is handling GLP, built from your labs, body composition, and symptom check-ins.
GLP tolerance scoreFirst result
Your body's response to GLP therapy, scored from labs, body comp, and symptoms.
Weight change paceFollow-up trend
Compares progress between tests
Body compositionIn-app scan
Track fat loss versus lean mass
SymptomsCheck-ins
Track what changes between tests
40+lab markers
Monthlyearly monitoring
Quarterlymaintenance checks
Not all weight loss is equal.
GLP medications can drop the number on the scale fast, but how much of that loss is fat versus muscle? Our GLP optimization program tracks both alongside your biomarkers, ensuring a stronger, healthier you.
Body composition
Fat down. Muscle stays.
Start240.7 lb
32%
68%
Month 1232.1 lb
30%
70%
Month 2224.8 lb
28%
72%
Today216.5 lb
25%
75%
-21.3 lb
fat lost - 89% of total
-2.7 lb
lean preserved - <15% loss
Biomarker panel
Ongoing health tracking.
HbA1c5.2% -0.6
Optimal
Testosterone612 ng/dL +18
Optimal
Ferritin142 ng/mL -9
Optimal
TSH2.1 mIU/L +0.1
Optimal
Side effects are often the first sign your intake has changed too much.
GLP therapy is known for GI side effects, but fatigue, brain fog, constipation, hair shedding, and muscle loss are often downstream signals of lower appetite, lower calories, and lower nutrient availability.
Nausea, diarrhea, vomiting, and constipation were common during treatment, especially around dose escalation.
Hair loss often lags behind under-fueling, protein gaps, iron depletion, vitamin D changes, or metabolic stress.
Monitoring goal
Catch adaptive changes before they become bigger problems.
Frequent bloodwork and body-composition tracking can surface nutrient depletion, excessive weight-loss pace, dehydration pressure, or metabolic imbalance early enough to adjust diet, supplementation, training, or dosing conversations proactively.
FatigueBrain fogConstipationHair sheddingMuscle loss
Fatigue and brain fog
Lower appetite can create sustained calorie deficits and under-fueling before you notice it day to day.
Tracked withGlucose, HbA1c, albumin, weight trend
What this helps withSpot early energy-availability patterns so nutrition and dose conversations happen sooner.
Hair shedding and nutrient gaps
Rapid weight loss plus lower protein, iron, B12, folate, or vitamin D intake can stress hair follicles.
Tracked withFerritin, iron studies, B12, folate, vitamin D, albumin, total protein
What this helps withTrack depletion risk and guide targeted nutrition or supplementation discussions.
Dehydration and constipation
Reduced thirst, nausea, and smaller meals can lower fluid and electrolyte intake.
Tracked withBUN, creatinine, eGFR, BUN:creatinine ratio
What this helps withCatch hydration pressure before it turns into worsening symptoms or kidney stress.
Muscle loss and rebound risk
Fast weight loss with insufficient protein or resistance training can reduce lean mass.
Tracked withBody-composition scanner, total protein, albumin, testosterone context
What this helps withSeparate healthy fat loss from lean-mass loss so training, protein, and pace can be adjusted.
Weight loss is the headline. Your biology is the story.
The panel is built for people already using, planning to use, or transitioning off GLP-based medication who want better trend visibility.
Confirm the wins beyond weight
HbA1c, estimated average glucose, C-peptide, and lipid trends help show whether your metabolism is changing in the right direction.
Catch important issues early
Track BUN, creatinine, eGFR, liver markers, bilirubin, & inflammation markers, and physical symptoms to flag changes that deserve attention during rapid weight loss.
Lose fat without giving up muscle
Weight alone can hide lean-mass loss. The SiPhox app helps you monitor body composition so you can adjust protein, training, and pace.
Keep nutrition and hormones in view
B12, ferritin, thyroid, and testosterone markers help explain fatigue, brain fog, recovery, libido, and mood during lower food intake.
Your whole health in one place.
Biomarkers, wearables, lab uploads, supplements, insights, actions and more, all in one dashboard.
Good afternoon, John.
6 systems improved since your last test, Liver Health the most at 9%. Nutritional is still out of range, so your plan targets it next. Let’s keep it going!
0%
Heart Health
+7%
BioAge 41·4 yrs under·Impressive!
Next steps4 items
Keep the loop going.
Share results with your doctor
They see new reports when you do
Connect your wearables
Sleep and activity over your labs
1:1 health coaching
Talk through your results with a coach
Explore programs
Coaching and added panels
Latest results · Jun 15, 2026 · vs your previous test
View reportWhat changed.
Heart HealthIn range
82%+7%
Metabolic HealthIn range
79%+6%
Kidney HealthIn range
84%+1%
Liver HealthIn range
80%+9%
Thyroid HealthIn range
77%+3%
NutritionalOut of range
58%+4%
BodyIn range
71%-2%
I'm tracking5 markers
25-(OH) Vitamin DPay attention
+1.4 vs last
27 ng/mL
ApoB:ApoA1 RatioOptimal
-0.03 vs last
0.34
TriglyceridesOptimal
no change
46 mg/dL
High-Sensitivity CRPOptimal
-0.32 vs last
0.96 mg/L
Testosterone, Total (Males)Optimal
+216.32 vs last
758.76 ng/dL
Actions that compound.
A routine built from your biomarkers. Take action to hit your outlook by your next test.
Care Actions
Consult Doctor for Elevated AST; Support Liver Health
See a doctor to discuss your elevated AST levels and, in the meantime, maintain a healthy lifestyle to support liver function.
ImprovesASTL1
Address Elevated Triglycerides:HDL for Health Management
• This weekSee a doctor to discuss your elevated Triglycerides:HDL ratio and its implications for insulin resistance and cardiovascular risk; in the meantime, monitor your levels and consider lifestyle changes to manage your health.
ImprovesTriglycerides:HDL RatioL1
Morning Stack
Sets the day.
3active
Taurine for Blood Sugar Optimization
• DailyTaurine has some of the better amino-acid data for metabolic health, with supportive evidence for improved glycemic control and insulin sensitivity, especially in obesity or diabetes.
Improves% Hemoglobin A1CEstimated Average Glucose (eAG)L1
Reduce SHBG through Lifestyle Changes
• DailyLifestyle measures may help support a healthier SHBG pattern. Focus on limiting heavy alcohol intake and eating enough total calories and protein, since excessive alcohol use and low protein intake have both been associated with higher SHBG. Strength training, quality sleep, and stress management can still support overall metabolic and hormonal health, but direct evidence that they lower high SHBG is limited.
ImprovesSHBGL3
Boost Vitamin D Levels
• DailyIncreasing sun exposure (15-20 minutes daily) or regularly taking an over-the-counter Vitamin D supplement can help boost your Vitamin D levels. The recommended dosage of Vitamin D intake ranges from 600 IU to 4000 IU per day as needed. If you already take vitamin D supplements, consider increasing the dosage.
Improves25-(OH) Vitamin DL1
What this improves
% Hemoglobin A1CTarget: < 5%5.6%
Estimated Average Glucose (eAG)Target: < 97114.02 mg/dL
SHBGTarget: 18.3-54.871.2 nmol/L
25-(OH) Vitamin DTarget: 40-7036 ng/mL
Future outlook
Where your active plan could move your health by your November panel.
Nutritional5874
Thyroid Health7790
Metabolic Health7986
Inflammation7076
Liver Health8085
Heart Health8285
Estimates use the biomarkers targeted by your active actions. Actual results may vary based on consistency, biology, and other health changes.
Included with your monitoring
Everything you need to track, understand, and optimize your health.
% Hemoglobin A1CLong-term blood sugar control
5.3 %
Estim. Avg Glu (eAG)Estimated average glucose
105 mg/dL
C-PeptideInsulin production signal
2.1 ng/mL
Cholesterol, TotalOverall cholesterol level
174 mg/dL
LDL Cholesterol"Bad" cholesterol
92 mg/dL
HDL Cholesterol"Good" cholesterol
62 mg/dL
TriglyceridesInsulin sensitivity marker
84 mg/dL
Triglycerides:HDL RatioCardiometabolic health signal
1.35
LDL-C:HDL-C RatioCholesterol balance
1.48
Total Cholesterol:HDL RatioHeart-health ratio
2.81
Apolipoprotein B (APOB)Atherogenic particle count
78 mg/dL
VLDL Cholesterol (Calc)Triglyceride-rich cholesterol
17 mg/dL
High-Sensitivity CRPLow-grade inflammation
1.1 mg/L
Alanine Aminotransferase (ALT)Liver enzyme
24 U/L
Aspartate Aminotransferase (AST)Liver and muscle enzyme
22 U/L
Alkaline Phosphatase (ALP)Liver and bile-duct marker
68 U/L
Total BilirubinLiver processing marker
0.7 mg/dL
Direct BilirubinBilirubin fraction
0.2 mg/dL
AlbuminProtein and liver status
4.6 g/dL
Sex Hormone-Binding Globulin (SHBG)Hormone transport protein
48 nmol/L
Blood Urea Nitrogen (BUN)Hydration and protein signal
18 mg/dL
CreatinineKidney and muscle context
0.82 mg/dL
eGFRKidney filtration estimate
103 mL/min/1.73 m2
BUN:Creatinine RatioHydration pressure signal
22
Thyroid Stimulating Hormone (TSH)Thyroid signaling
1.8 uIU/mL
Free Thyroxine (Free T4)Available thyroid hormone
1.2 ng/dL
Testosterone, Total (Males)Total androgen level
540 ng/dL
Testosterone, Free (calc)Bioavailable testosterone
11.8 pg/mL
% Free TestosteroneActive testosterone fraction
2.2 %
CortisolStress-axis marker
12.4 ug/dL
25-(OH) Vitamin DVitamin D status
46 ng/mL
Vitamin B12Energy and nerve nutrient
612 pg/mL
FolateB-vitamin status
12.8 ng/mL
FerritinIron storage
72 ng/mL
IronCirculating iron
92 ug/dL
Unsaturated iron-binding capacity test (UIBC)Iron-binding reserve
230 ug/dL
Iron Bind.Cap.(TIBC)Total iron-binding capacity
322 ug/dL
Iron SaturationIron availability
29 %
Total ProteinProtein status
7.1 g/dL
Comprehensive Biomarker Testing
Test your biomarkers with comprehensive panels without leaving home.
Chat with Sai
24/7 Health Assistant
Chat with Sai, about your results, health and longevity.
Lion's Mane
Berberine
NMN
Apigenin
Glycine
L-Citrulline
Beta-Alanine
Beetroot Extract
Grape Seed Extract
Phosphatidylserine
Lion's Mane
Berberine
NMN
Apigenin
Glycine
L-Citrulline
Beta-Alanine
Beetroot Extract
Grape Seed Extract
Phosphatidylserine
Iron
Calcium
Vitamin K2
Selenium
Folate
Vitamin D3
NAD+
Omega-3
Quercetin
Green Tea Extract
Iron
Calcium
Vitamin K2
Selenium
Folate
Vitamin D3
NAD+
Omega-3
Quercetin
Green Tea Extract
L-Theanine
Magnesium
Rhodiola
Ginseng
Biotin
Vitamin B12
Alpha Lipoic Acid
Glucosamine
Chondroitin
Probiotics
L-Theanine
Magnesium
Rhodiola
Ginseng
Biotin
Vitamin B12
Alpha Lipoic Acid
Glucosamine
Chondroitin
Probiotics
Zinc
MSM
Collagen
L-Glutamine
Creatine
BCAA
Vitamin C
L-Arginine
Taurine
Melatonin
Zinc
MSM
Collagen
L-Glutamine
Creatine
BCAA
Vitamin C
L-Arginine
Taurine
Melatonin
GABA
St. John's Wort
Valerian Root
CoQ10
Milk Thistle
Spirulina
Turmeric
Chlorella
Wheatgrass
Maca Root
GABA
St. John's Wort
Valerian Root
CoQ10
Milk Thistle
Spirulina
Turmeric
Chlorella
Wheatgrass
Maca Root
Ginkgo Biloba
Saw Palmetto
Black Cohosh
Evening Primrose
Garlic Extract
Ashwagandha
Echinacea
Vitamin E
Chromium
Resveratrol
Ginkgo Biloba
Saw Palmetto
Black Cohosh
Evening Primrose
Garlic Extract
Ashwagandha
Echinacea
Vitamin E
Chromium
Resveratrol
Inositol
Bromelain
Astaxanthin
PQQ
Psyllium Husk
Boswellia
Bacopa Monnieri
Hawthorn Berry
Manganese
Copper
Inositol
Bromelain
Astaxanthin
PQQ
Psyllium Husk
Boswellia
Bacopa Monnieri
Hawthorn Berry
Manganese
Copper
Nutritional Optimization
Catch nutritional deficiencies early.
Apple Watch
Sleep: 7.2h
HRV: 45ms
Resting HR: 62 bpm
Oura Ring
Sleep Score: 87
Readiness: 92
Body Temp: +0.2°C
Fitbit
Active Zone: 142 min
Calories: 2,341
Sleep Score: 78
Wearable Sync
Connect your wearables to track sleep, activity & glucose.
Set your body-composition baseline, then watch what changes.
Ensure you are losing weight in a healthy way by connecting fat loss, lean mass, symptoms, and biomarkers in one GLP optimization loop.
First testSet your starting point
Capture your weight, body composition, labs, hydration, and nutrition before you compare trends.
Follow-up testsConfirm healthy loss
See whether weight loss is coming from fat, not muscle, while symptoms and biomarkers stay on track.
Body scansSeparate fat from muscle
Track fat loss and lean-mass preservation alongside your biomarker trends.
Body-composition scanner
Track fat loss and muscle preservation beside your biomarker trends.
Body-composition trendFat loss vs lean mass
Wearables and CGM contextConnect where available
Action planPersonalized after results
The markers that matter for GLP therapy tolerance.
The panel focuses on the markers and explanations that matter most when appetite, weight, hydration, and body composition are changing. Start with key markers, then explore the full panel by category.
Key markers
% Hemoglobin A1C
Shows your average blood sugar over the past three months. GLP-based therapies often improve this dramatically, so tracking it lets you see one of the clearest wins from treatment.
C-Peptide
Shows how much insulin your body is producing. Useful context when appetite, blood sugar control, and metabolic demand are changing.
Apolipoprotein B (APOB)
Counts the particles most tied to atherosclerotic risk, giving a sharper signal than LDL alone.
High-Sensitivity CRP
Tracks low-grade inflammation, a useful signal when metabolic risk and body composition are changing.
Alanine Aminotransferase (ALT)
A liver enzyme that can improve as fatty-liver stress decreases during weight loss.
Blood Urea Nitrogen (BUN)
Helps show whether you may be dehydrated, especially during dose increases when nausea and reduced fluid intake can creep up.
Vitamin B12
An essential nutrient that can drop when you eat less meat, fish, dairy, and eggs. Low B12 can cause fatigue and brain fog.
Ferritin
Your iron storage. Especially important for women because low iron can quickly lead to fatigue and lower exercise capacity.
In-app body-composition scanner
Tracks muscle versus fat instead of only total weight. The goal on therapy is to lose fat while keeping muscle.
Real users. Real experiences.
Join over 50,000 individuals who have taken control of their health through data-driven insights and actions.
Colin's Story
SiPhox caught what no one saw
Chanda's Story
A dangerous heart risk came to light
Ben's Story
Testing uncovered type 1 diabetes
Jonathan's Story
A shockingly high bioage revealed the truth
Your privacy first. Always.
Enterprise-grade security
Our servers meet or exceed all applicable data protection and privacy requirements. Your sensitive information is safeguarded by state-of-the-art security measures.
Zero Personal Data Selling Policy
We have a strict no-sell policy for your personal information. Your data remains yours, period.
Complete Data Control
Delete your personal information from our servers at any time. We respect your right to data ownership and provide easy-to-use tools for data management.
Backed by leading experts in health optimization
Pavel Korecky, MD
Director of Clinical Product Operations
Daniel Kaplan, PhD
Director of Assay Development
Paul Thompson, MD
Advisor, Cardiology
Ben Bikman, PhD
Advisor, Metabolic Research
Pika Ksela, MD
Health Programs Lead
David Nguyen, MD
Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD
Director of Clinical Product Operations
Daniel Kaplan, PhD
Director of Assay Development
Paul Thompson, MD
Advisor, Cardiology
Ben Bikman, PhD
Advisor, Metabolic Research
Pika Ksela, MD
Health Programs Lead
David Nguyen, MD
Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD
Director of Clinical Product Operations
Daniel Kaplan, PhD
Director of Assay Development
Paul Thompson, MD
Advisor, Cardiology
Ben Bikman, PhD
Advisor, Metabolic Research
Pika Ksela, MD
Health Programs Lead
David Nguyen, MD
Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD
Director of Clinical Product Operations
Daniel Kaplan, PhD
Director of Assay Development
Paul Thompson, MD
Advisor, Cardiology
Ben Bikman, PhD
Advisor, Metabolic Research
Pika Ksela, MD
Health Programs Lead
David Nguyen, MD
Advisor, Hematology and Cancer Prevention
Pavel Korecky, MD
Director of Clinical Product Operations
Daniel Kaplan, PhD
Director of Assay Development
Paul Thompson, MD
Advisor, Cardiology
Ben Bikman, PhD
Advisor, Metabolic Research
Pika Ksela, MD
Health Programs Lead